Abstract
To select a movement, specific neuronal populations controlling particular features of that movement need to be activated, whereas other populations are downregulated. The selective (dis)inhibition of cortical sensorimotor populations is governed by rhythmic neural activity in the alpha (8 –12 Hz) and beta (15–25 Hz) frequency range. However, it is unclear whether and how these rhythms contribute independently to motor behavior. Building on a recent dissociation of the sensorimotor alpha- and beta-band rhythms, we test the hypothesis that the beta-band rhythm governs the disinhibition of task-relevant neuronal populations, whereas the alpha-band rhythm suppresses neurons that may interfere with task performance. Cortical alpha- and beta-band rhythms were manipulated with transcranial alternating current stimulation (tACS) while human participants selected how to grasp an object. Stimulation was applied at either 10 or 20 Hz and was imposed on the sensorimotor cortex contralaterally or ipsilaterally to the grasping hand. In line with task-induced changes in endogenous spectral power, the effect of the tACS intervention depended on the frequency and site of stimulation. Whereas tACS stimulation generally increased movement selection times, 10 Hz stimulation led to relatively faster selection times when applied to the hemisphere ipsilateral to the grasping hand, compared with other stimulation conditions. These effects occurred selectively when multiple movements were considered. These observations functionally differentiate the causal contribution of alpha- and beta-band oscillations to movement selection. The findings suggest that sensorimotor beta-band rhythms disinhibit task-relevant populations, whereas alpha-band rhythms inhibit neuronal populations that could interfere with movement selection.
Original language | English |
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Pages (from-to) | 8726-8733 |
Number of pages | 8 |
Journal | Journal of Neuroscience |
Volume | 36 |
Issue number | 33 |
DOIs | |
Publication status | Published - 17 Aug 2016 |
Bibliographical note
Funding Information:This work was supported by The Netherlands Organisation for Scientific Research (NWO Brain and Cognition 433-09-248). We thank Ole Jensen and Ian Cameron for useful comments on the manuscript.
Publisher Copyright:
© 2016 the authors.
Keywords
- Alpha beta oscillations
- Motor imagery
- Movement selection
- Noninvasive brain stimulation
- Sensorimotor
ASJC Scopus subject areas
- General Neuroscience