Hypoplastic left heart syndrome

David Barron, Mark Kilby, B Davies, John Wright, Timothy Jones, William Brawn

Research output: Contribution to journalArticle

133 Citations (Scopus)


Hypoplastic left heart syndrome is a rare congenital heart defect in which the left side of the heart is underdeveloped. Surgical management of hypoplastic left heart syndrome has changed the prognosis of the condition that was previously regarded as fatal. We discuss surgical strategies based on staged procedures, with the right ventricle supporting both systemic and pulmonary circulation. We also discuss other management options, such as neonatal transplantation and the recent innovation of hybrid techniques. Surgical techniques and the understanding of the pathophysiology of this condition have been at the forefront of neonatal cardiac surgery and intensive care. The management of the syndrome remains a challenge because affected children grow into adolescence and adulthood posing various new problems and demands.
Original languageEnglish
Pages (from-to)551-564
Number of pages14
Issue number9689
Publication statusPublished - 1 Aug 2009


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