Giant cell arteritis: reviewing the advancing diagnostics and management

Edward J. Bilton, Susan P. Mollan*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

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Abstract

Giant Cell Arteritis (GCA) is well known to be a critical ischaemic disease that requires immediate medical recognition to initiate treatment and where one in five people still suffer visual loss. The immunopathophysiology has continued to be characterised, and the influencing of ageing in the development of GCA is beginning to be understood. Recent national and international guidelines have supported the directed use of cranial ultrasound to reduce diagnostic delay and improve clinical outcomes. Immediate high dose glucocorticoids remain the standard emergency treatment for GCA, with a number of targeted agents that have been shown in clinical trials to have superior clinical efficacy and steroid sparing effects. The aim of this review was to present the latest advances in GCA that have the potential to influence routine clinical practice.
Original languageEnglish
Pages (from-to)2365-2373
Number of pages9
JournalEye
Volume37
Issue number12
Early online date14 Feb 2023
DOIs
Publication statusPublished - Aug 2023

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