Factors influencing perinatal outcomes in women with preterm preeclampsia: A secondary analysis of the PHOENIX trial

Jessica Fleminger; Kate Duhig; Paul T Seed; Peter Brocklehurst; Marcus Green; Edmund Juszczak; Neil Marlow; Andrew Shennan; Lucy Chappell

doi:10.1016/j.preghy.2021.10.002

Factors influencing perinatal outcomes in women with preterm preeclampsia: A secondary analysis of the PHOENIX trial

Jessica Fleminger, Kate Duhig, Paul T Seed, Peter Brocklehurst, Marcus Green, Edmund Juszczak, Neil Marlow, Andrew Shennan, Lucy Chappell

Birmingham Clinical Trials Unit

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Abstract

This secondary analysis of the PHOENIX trial (evaluating planned delivery against expectant management in late preterm preeclampsia) demonstrates that in women who started induction of labour, 63% of women delivered vaginally (56% at 34 weeks' gestation). Compared to expectant management, planned delivery was associated with higher rates of neonatal unit admission for prematurity (but lower proportions of small-for-gestational age infants); length of neonatal unit stay and neonatal morbidity (including respiratory support) were similar across both intervention groups at all gestational windows. Neonatal unit admission was increased by earlier gestation at delivery, development of severe preeclampsia, and being small-for-gestational age.

Original language	English
Pages (from-to)	91-93
Number of pages	3
Journal	Pregnancy Hypertension
Volume	26
Early online date	13 Oct 2021
DOIs	https://doi.org/10.1016/j.preghy.2021.10.002
Publication status	Published - Dec 2021

Bibliographical note

Keywords

Delivery, Obstetric/statistics & numerical data
Female
Follow-Up Studies
Humans
Infant, Premature
Intensive Care Units, Neonatal/statistics & numerical data
Labor, Induced/statistics & numerical data
Pre-Eclampsia/physiopathology
Pregnancy
Pregnancy Outcome/epidemiology
Watchful Waiting/statistics & numerical data

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title = "Factors influencing perinatal outcomes in women with preterm preeclampsia: A secondary analysis of the PHOENIX trial",

abstract = "This secondary analysis of the PHOENIX trial (evaluating planned delivery against expectant management in late preterm preeclampsia) demonstrates that in women who started induction of labour, 63% of women delivered vaginally (56% at 34 weeks' gestation). Compared to expectant management, planned delivery was associated with higher rates of neonatal unit admission for prematurity (but lower proportions of small-for-gestational age infants); length of neonatal unit stay and neonatal morbidity (including respiratory support) were similar across both intervention groups at all gestational windows. Neonatal unit admission was increased by earlier gestation at delivery, development of severe preeclampsia, and being small-for-gestational age.",

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author = "Jessica Fleminger and Kate Duhig and Seed, {Paul T} and Peter Brocklehurst and Marcus Green and Edmund Juszczak and Neil Marlow and Andrew Shennan and Lucy Chappell",

note = "Copyright {\textcopyright} 2021 The Authors.",

year = "2021",

month = dec,

doi = "10.1016/j.preghy.2021.10.002",

language = "English",

volume = "26",

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AU - Seed, Paul T

AU - Brocklehurst, Peter

AU - Green, Marcus

AU - Juszczak, Edmund

AU - Marlow, Neil

AU - Shennan, Andrew

AU - Chappell, Lucy

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AB - This secondary analysis of the PHOENIX trial (evaluating planned delivery against expectant management in late preterm preeclampsia) demonstrates that in women who started induction of labour, 63% of women delivered vaginally (56% at 34 weeks' gestation). Compared to expectant management, planned delivery was associated with higher rates of neonatal unit admission for prematurity (but lower proportions of small-for-gestational age infants); length of neonatal unit stay and neonatal morbidity (including respiratory support) were similar across both intervention groups at all gestational windows. Neonatal unit admission was increased by earlier gestation at delivery, development of severe preeclampsia, and being small-for-gestational age.

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KW - Follow-Up Studies

KW - Humans

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KW - Labor, Induced/statistics & numerical data

KW - Pre-Eclampsia/physiopathology

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KW - Pregnancy Outcome/epidemiology

KW - Watchful Waiting/statistics & numerical data

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JO - Pregnancy Hypertension

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ER -

Factors influencing perinatal outcomes in women with preterm preeclampsia: A secondary analysis of the PHOENIX trial

Abstract

Bibliographical note

Keywords

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Cite this