ERK1/2 and p38 cooperate to induce a p21CIP1-dependent G1 cell cycle arrest

Keyphrases

• P21Cip1 100%
• ERK2 100%
• G1 Cell Cycle Arrest 100%
• Cell Cycle Re-entry 60%
• Selective Activation 40%
• G1 Arrest 40%
• Methylation 20%
• Mitogen-activated Protein Kinase 20%
• Wild-type p53 20%
• Sigma Phase 20%
• Quiescent Cells 20%
• Decreased Expression 20%
• Cell Cycle Arrest 20%
• Distinct Mechanism 20%
• Restimulation 20%
• Cyclin D1 (CCND1) 20%
• Potentiation 20%
• Strongest Activations 20%
• Stress-activated Protein Kinase 20%
• Cdc25 20%
• P21 Expression 20%
• 3T3 Cells 20%
• JNK1 20%
• CDK2 Activity 20%
• P38α 20%

Biochemistry, Genetics and Molecular Biology

• G1/S Transition 100%
• Cell Cycle 60%
• Wild Type 40%
• extracellular signal regulated kinase 40%
• C-Jun N-Terminal Kinases 40%
• Methylation 20%
• P53 20%
• P21 20%
• S Phase 20%
• Cyclin-Dependent Kinase 20%
• Cyclin D1 20%
• Cell Cycle Arrest 20%
• Cell Cycle Checkpoint 20%

Immunology and Microbiology

• G1 Phase Cell Cycle Checkpoint 100%
• Cell Cycle 60%
• Wild Type 40%
• Mitogen 20%
• P53 20%
• Methylation 20%
• Cell Cycle Checkpoint 20%
• Cell Cycle Arrest 20%
• Cyclin D1 20%