Efficient Multicomponent Active Template Synthesis of Catenanes

James E.M. Lewis; Florian Modicom; Stephen M. Goldup

doi:10.1021/jacs.8b01602

Efficient Multicomponent Active Template Synthesis of Catenanes

James E.M. Lewis, Florian Modicom, Stephen M. Goldup^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

We describe a simple and high yielding active template synthesis of [2]catenanes. In addition to mechanical bond formation using a single premacrocycle bearing an azide and alkyne moiety, our method is also suitable for the co-macrocyclization of readily available bis-alkyne and bis-azide comonomers and even short alkyne/azide components which oligomerize prior to mechanical bond formation.

Original language	English
Pages (from-to)	4787-4791
Number of pages	5
Journal	Journal of the American Chemical Society
Volume	140
Issue number	14
DOIs	https://doi.org/10.1021/jacs.8b01602
Publication status	Published - 11 Apr 2018

Bibliographical note

Funding Information:
The authors thank Fluorochem for the gift of reagents. J.E.M.L. thanks the European Union’s Horizon 2020 programme for a Marie Skłodowska-Curie Fellowship (agreement no. 660731). F.M. thanks the EPSRC (EP/L505067/1) for funding. S.M.G. acknowledges funding from the European Research Council (Consolidator Grant Agreement no. 724987).

Publisher Copyright:
© 2018 American Chemical Society.

ASJC Scopus subject areas

Catalysis
General Chemistry
Biochemistry
Colloid and Surface Chemistry

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abstract = "We describe a simple and high yielding active template synthesis of [2]catenanes. In addition to mechanical bond formation using a single premacrocycle bearing an azide and alkyne moiety, our method is also suitable for the co-macrocyclization of readily available bis-alkyne and bis-azide comonomers and even short alkyne/azide components which oligomerize prior to mechanical bond formation.",

author = "Lewis, {James E.M.} and Florian Modicom and Goldup, {Stephen M.}",

note = "Funding Information: The authors thank Fluorochem for the gift of reagents. J.E.M.L. thanks the European Union{\textquoteright}s Horizon 2020 programme for a Marie Sk{\l}odowska-Curie Fellowship (agreement no. 660731). F.M. thanks the EPSRC (EP/L505067/1) for funding. S.M.G. acknowledges funding from the European Research Council (Consolidator Grant Agreement no. 724987). Publisher Copyright: {\textcopyright} 2018 American Chemical Society.",

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AU - Modicom, Florian

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N2 - We describe a simple and high yielding active template synthesis of [2]catenanes. In addition to mechanical bond formation using a single premacrocycle bearing an azide and alkyne moiety, our method is also suitable for the co-macrocyclization of readily available bis-alkyne and bis-azide comonomers and even short alkyne/azide components which oligomerize prior to mechanical bond formation.

AB - We describe a simple and high yielding active template synthesis of [2]catenanes. In addition to mechanical bond formation using a single premacrocycle bearing an azide and alkyne moiety, our method is also suitable for the co-macrocyclization of readily available bis-alkyne and bis-azide comonomers and even short alkyne/azide components which oligomerize prior to mechanical bond formation.

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Efficient Multicomponent Active Template Synthesis of Catenanes

Abstract

Bibliographical note

ASJC Scopus subject areas

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