Effective--a database of predicted secreted bacterial proteins

Marc-André Jehl; Roland Arnold; Thomas Rattei

doi:10.1093/nar/gkq1154

Effective--a database of predicted secreted bacterial proteins

Marc-André Jehl, Roland Arnold, Thomas Rattei

Cancer and Genomic Sciences

Research output: Contribution to journal › Article › peer-review

77 Citations (Scopus)

Abstract

Protein secretion is a key virulence mechanism of pathogenic and symbiotic bacteria, which makes the investigation of secreted proteins ('effectors') crucial for understanding the molecular bacterium-host interactions. Effective (http://effectors.org) is a database of predicted bacterial secreted proteins, implementing two complementary prediction strategies for protein secretion: the identification of eukaryotic-like protein domains and the recognition of signal peptides in amino acid sequences. The Effective web portal provides user-friendly tools for browsing and retrieving comprehensive precalculated predictions for whole bacterial genomes as well as for the interactive prediction of effectors in user-provided protein sequences.

Original language	English
Pages (from-to)	D591-5
Journal	Nucleic Acids Research
Volume	39
Issue number	Database issue
DOIs	https://doi.org/10.1093/nar/gkq1154
Publication status	Published - Jan 2011

Keywords

Bacterial Proteins
Databases, Protein
Genome, Bacterial
Protein Sorting Signals
Protein Structure, Tertiary
Journal Article
Research Support, Non-U.S. Gov't

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10.1093/nar/gkq1154

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KW - Bacterial Proteins

KW - Databases, Protein

KW - Genome, Bacterial

KW - Protein Sorting Signals

KW - Protein Structure, Tertiary

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

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SP - D591-5

JO - Nucleic Acids Research

JF - Nucleic Acids Research

IS - Database issue

ER -

Effective--a database of predicted secreted bacterial proteins

Abstract

Keywords

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