Diagnosis and treatment of Cushing's disease in children

Martin O Savage; Renuka P Dias; Li F Chan; Farhad Afshar; Nicolas P Plowman; Matthew Matson; Ashley B Grossman; Helen L Storr

doi:10.1159/000262535

Diagnosis and treatment of Cushing's disease in children

Martin O Savage, Renuka P Dias, Li F Chan, Farhad Afshar, Nicolas P Plowman, Matthew Matson, Ashley B Grossman, Helen L Storr

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3 Citations (Scopus)

Abstract

Cushing's disease (CD) is rare in the paediatric age range, but presents a diagnostic and therapeutic challenge. Most paediatric endocrinologists have limited experience managing children or adolescents with CD and thus benefit from close consultation with adult colleagues. A diagnostic protocol for investigation is required which broadly follows the model for adult patients. Treatment strategies for CD are described and critically appraised. The management of paediatric CD patients after cure also presents challenges for optimizing growth, bone health, reproduction and body composition from childhood into and during adult life.

Original language	English
Pages (from-to)	134-45
Number of pages	12
Journal	Endocrine development
Volume	17
DOIs	https://doi.org/10.1159/000262535
Publication status	Published - 2010

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abstract = "Cushing's disease (CD) is rare in the paediatric age range, but presents a diagnostic and therapeutic challenge. Most paediatric endocrinologists have limited experience managing children or adolescents with CD and thus benefit from close consultation with adult colleagues. A diagnostic protocol for investigation is required which broadly follows the model for adult patients. Treatment strategies for CD are described and critically appraised. The management of paediatric CD patients after cure also presents challenges for optimizing growth, bone health, reproduction and body composition from childhood into and during adult life.",

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AU - Savage, Martin O

AU - Dias, Renuka P

AU - Chan, Li F

AU - Afshar, Farhad

AU - Plowman, Nicolas P

AU - Matson, Matthew

AU - Grossman, Ashley B

AU - Storr, Helen L

PY - 2010

Y1 - 2010

N2 - Cushing's disease (CD) is rare in the paediatric age range, but presents a diagnostic and therapeutic challenge. Most paediatric endocrinologists have limited experience managing children or adolescents with CD and thus benefit from close consultation with adult colleagues. A diagnostic protocol for investigation is required which broadly follows the model for adult patients. Treatment strategies for CD are described and critically appraised. The management of paediatric CD patients after cure also presents challenges for optimizing growth, bone health, reproduction and body composition from childhood into and during adult life.

AB - Cushing's disease (CD) is rare in the paediatric age range, but presents a diagnostic and therapeutic challenge. Most paediatric endocrinologists have limited experience managing children or adolescents with CD and thus benefit from close consultation with adult colleagues. A diagnostic protocol for investigation is required which broadly follows the model for adult patients. Treatment strategies for CD are described and critically appraised. The management of paediatric CD patients after cure also presents challenges for optimizing growth, bone health, reproduction and body composition from childhood into and during adult life.

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DO - 10.1159/000262535

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SN - 1662-2979

VL - 17

SP - 134

EP - 145

JO - Endocrine development

JF - Endocrine development

ER -

Diagnosis and treatment of Cushing's disease in children

Abstract

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