Data supporting the functional role of Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) in B cell lymphoma cell line cells

Lou-Ella M. M. Alexander; January Watters; Jessica A. Reusch; Michelle Maurin; Brook S. Nepon-Sixt; Katerina Vrzalikova; Mark G. Alexandrow; Paul G. Murray; Kenneth L. Wright

doi:10.1016/j.dib.2017.09.042

Data supporting the functional role of Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) in B cell lymphoma cell line cells

Lou-Ella M. M. Alexander, January Watters, Jessica A. Reusch, Michelle Maurin, Brook S. Nepon-Sixt, Katerina Vrzalikova, Mark G. Alexandrow, Paul G. Murray, Kenneth L. Wright

Cancer and Genomic Sciences

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

The data presented here are related to the research article entitled “Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival” (Alexander et al., 2017) [1]. The cited research article characterizes Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) expression in the B cell compartment and functional dependence in B lymphoma cell lines. This data report describes the mRNA expression pattern in a panel of cell lines representing the B cell compartment, supplementing the protein expression data presented in the associated research report. In addition, a reanalysis is presented of publicly available mRNA expression data from primary murine B cells to reveal dynamic regulation of the ELL family members post LPS stimulation (Barwick et al., 2016) [2]. The effect of ELL3 depletion on cell morphology, latent Epstein Barr Virus (EBV) lytic replication and differentiation markers in a Burkitt's lymphoma (BL) cell line cells are presented.

Original language	English
Pages (from-to)	222-227
Journal	Data in Brief
Volume	15
Early online date	22 Sept 2017
DOIs	https://doi.org/10.1016/j.dib.2017.09.042
Publication status	Published - 1 Dec 2017

Keywords

ELL3
Transcription elongation
B-cell lymphoma
cell division
EBV

Access to Document

10.1016/j.dib.2017.09.042Licence: Creative Commons: Attribution (CC BY)

http://www.sciencedirect.com/science/article/pii/S2352340917304730Licence: Creative Commons: Attribution (CC BY)

Cite this

@article{f6a1f6730c194cf78e67b75d018fd21a,

title = "Data supporting the functional role of Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) in B cell lymphoma cell line cells",

abstract = "The data presented here are related to the research article entitled “Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival” (Alexander et al., 2017) [1]. The cited research article characterizes Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) expression in the B cell compartment and functional dependence in B lymphoma cell lines. This data report describes the mRNA expression pattern in a panel of cell lines representing the B cell compartment, supplementing the protein expression data presented in the associated research report. In addition, a reanalysis is presented of publicly available mRNA expression data from primary murine B cells to reveal dynamic regulation of the ELL family members post LPS stimulation (Barwick et al., 2016) [2]. The effect of ELL3 depletion on cell morphology, latent Epstein Barr Virus (EBV) lytic replication and differentiation markers in a Burkitt's lymphoma (BL) cell line cells are presented.",

keywords = "ELL3 , Transcription elongation , B-cell lymphoma , cell division , EBV",

author = "Alexander, {Lou-Ella M. M.} and January Watters and Reusch, {Jessica A.} and Michelle Maurin and Nepon-Sixt, {Brook S.} and Katerina Vrzalikova and Alexandrow, {Mark G.} and Murray, {Paul G.} and Wright, {Kenneth L.}",

year = "2017",

month = dec,

day = "1",

doi = "10.1016/j.dib.2017.09.042",

language = "English",

volume = "15",

pages = "222--227",

journal = "Data in Brief",

issn = "2352-3409",

publisher = "Elsevier",

}

TY - JOUR

T1 - Data supporting the functional role of Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) in B cell lymphoma cell line cells

AU - Alexander, Lou-Ella M. M.

AU - Watters, January

AU - Reusch, Jessica A.

AU - Maurin, Michelle

AU - Nepon-Sixt, Brook S.

AU - Vrzalikova, Katerina

AU - Alexandrow, Mark G.

AU - Murray, Paul G.

AU - Wright, Kenneth L.

PY - 2017/12/1

Y1 - 2017/12/1

N2 - The data presented here are related to the research article entitled “Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival” (Alexander et al., 2017) [1]. The cited research article characterizes Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) expression in the B cell compartment and functional dependence in B lymphoma cell lines. This data report describes the mRNA expression pattern in a panel of cell lines representing the B cell compartment, supplementing the protein expression data presented in the associated research report. In addition, a reanalysis is presented of publicly available mRNA expression data from primary murine B cells to reveal dynamic regulation of the ELL family members post LPS stimulation (Barwick et al., 2016) [2]. The effect of ELL3 depletion on cell morphology, latent Epstein Barr Virus (EBV) lytic replication and differentiation markers in a Burkitt's lymphoma (BL) cell line cells are presented.

AB - The data presented here are related to the research article entitled “Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival” (Alexander et al., 2017) [1]. The cited research article characterizes Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) expression in the B cell compartment and functional dependence in B lymphoma cell lines. This data report describes the mRNA expression pattern in a panel of cell lines representing the B cell compartment, supplementing the protein expression data presented in the associated research report. In addition, a reanalysis is presented of publicly available mRNA expression data from primary murine B cells to reveal dynamic regulation of the ELL family members post LPS stimulation (Barwick et al., 2016) [2]. The effect of ELL3 depletion on cell morphology, latent Epstein Barr Virus (EBV) lytic replication and differentiation markers in a Burkitt's lymphoma (BL) cell line cells are presented.

KW - ELL3

KW - Transcription elongation

KW - B-cell lymphoma

KW - cell division

KW - EBV

U2 - 10.1016/j.dib.2017.09.042

DO - 10.1016/j.dib.2017.09.042

M3 - Article

SN - 2352-3409

VL - 15

SP - 222

EP - 227

JO - Data in Brief

JF - Data in Brief

ER -

Data supporting the functional role of Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) in B cell lymphoma cell line cells

Abstract

Keywords

Access to Document

Fingerprint

Cite this