Children with cancer are not at increased risk of severe SARS-CoV-2 infection; however, adults with haematological malignancies have increased risk of severe infections compared with non-haematological malignancies.
We compared patients with haematological and non-haematological malignancies enrolled in the UK Paediatric Coronavirus Cancer Monitoring Project between 12 March 2020 and 16 February 2021. Children who received stem cell transplantation were excluded.
Only 2/62 patients with haematological malignancy had severe/critical infections, with an OR of 0.5 for patients with haematological compared with non-haematological malignancies.
Children with haematological malignancies are at no greater risk of severe SARS-CoV-2 infection than those with non-haematological malignancies.
Data availability statement
Data are available on reasonable request. The database contains de-identified participant data which are anonymised at source prior to upload. Reasonable requests for data sharing will be considered.
Bibliographical notePublisher Copyright:
© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ.
University of Birmingham provided the database and bio-informatics support, GCM is partially funded by a Cancer Research UK grant (A30259). This paper presents independent research supported by the National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre (Grant Reference Number BRC-1215-20009).
- Data collection
- data collection
- Severity of Illness Index
- Risk Factors
- Risk Assessment/statistics & numerical data
- Child, Preschool
- Hematologic Neoplasms/epidemiology
- Cohort Studies
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health