Complicated Urinary Tract Infection in a Tertiary Care Center in South India

Context: Knowledge of microbiology and antibiotic susceptibility of complicated urinary tract infection (cUTI) is essential for defining the empirical treatment Aims: 1) To find out the common presenting symptomatology associated with cUTI 2) To determine the distribution of bacterial strains isolated from cUTI 3) To identify Extended Spectrum Beta Lactamase (ESBL) producers in the different populations of uropathogens 4)To determine the resistance pattern of these bacteria. Settings and Design: Prospective study was done in a tertiary care centre in Bangalore from l January, 2008 to 31st December, 2008. Methods and Material: The study included all the patients who were admitted or visited the outpatient departments in the hospital and had urinary tract infection confirmed by positive urine culture reports. Results: Dysuria (31.4%) was the most common symptom with cUTI patients. Escherichia coli accounted to 65.7% of the total infection. 66.78% of the total Escherichia coli were ESBL positive. A high degree of resistance was recorded for first generation fluoroquinolones (76.9%) among the isolates in our study. Conclusions: A unified antibiotic protocol is necessitated to limit this increase and reduce the squeal of cUTI.