Co-ordination of intrathymic self-representation

Graham Anderson; William E Jenkinson

doi:10.1038/ni.3251

Co-ordination of intrathymic self-representation

Graham Anderson, William E Jenkinson

Immunology and Immunotherapy

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Intrathymic expression of self antigens is key for central tolerance. RNA-sequencing analysis of tissue-restricted antigens in individual medullary thymic epithelial cells reveals co-ordination in the gene-expression patterns that ensures effective self-representation for the production of self-tolerant T cells.

Original language	English
Pages (from-to)	895-896
Number of pages	2
Journal	Nature Immunology
Volume	16
Issue number	9
Early online date	19 Aug 2015
DOIs	https://doi.org/10.1038/ni.3251
Publication status	Published - Sept 2015

Access to Document

10.1038/ni.3251Licence: None: All rights reserved

Role of the Lymphotoxin signaling axis in the regulation of thymic microenvironments:Implications for age-associated thymic atrophy
Jenkinson, W.
Biotechnology & Biological Sciences Research Council
1/05/15 → 30/04/18
Project: Research Councils

Cite this

@article{e80bdbedc86040c4baeca4b335606646,

title = "Co-ordination of intrathymic self-representation",

abstract = "Intrathymic expression of self antigens is key for central tolerance. RNA-sequencing analysis of tissue-restricted antigens in individual medullary thymic epithelial cells reveals co-ordination in the gene-expression patterns that ensures effective self-representation for the production of self-tolerant T cells.",

author = "Graham Anderson and Jenkinson, {William E}",

year = "2015",

month = sep,

doi = "10.1038/ni.3251",

language = "English",

volume = "16",

pages = "895--896",

journal = "Nature Immunology",

issn = "1529-2908",

publisher = "Nature Publishing Group",

number = "9",

}

TY - JOUR

T1 - Co-ordination of intrathymic self-representation

AU - Anderson, Graham

AU - Jenkinson, William E

PY - 2015/9

Y1 - 2015/9

N2 - Intrathymic expression of self antigens is key for central tolerance. RNA-sequencing analysis of tissue-restricted antigens in individual medullary thymic epithelial cells reveals co-ordination in the gene-expression patterns that ensures effective self-representation for the production of self-tolerant T cells.

AB - Intrathymic expression of self antigens is key for central tolerance. RNA-sequencing analysis of tissue-restricted antigens in individual medullary thymic epithelial cells reveals co-ordination in the gene-expression patterns that ensures effective self-representation for the production of self-tolerant T cells.

U2 - 10.1038/ni.3251

DO - 10.1038/ni.3251

M3 - Article

C2 - 26287586

SN - 1529-2908

VL - 16

SP - 895

EP - 896

JO - Nature Immunology

JF - Nature Immunology

IS - 9

ER -

Co-ordination of intrathymic self-representation

Abstract

Access to Document

Fingerprint

Projects

Role of the Lymphotoxin signaling axis in the regulation of thymic microenvironments:Implications for age-associated thymic atrophy

Cite this