Clinical Applications of Anterior Segment Optical Coherence Tomography: An Updated Review

Yu Jeat Chong; Matthew Azzopardi; Gulmeena Hussain; Alberto Recchioni; Jaishree Gandhewar; Constantinos Loizou; Ioannis Giachos; Ankur Barua; Darren S. J. Ting

doi:10.3390/diagnostics14020122

Clinical Applications of Anterior Segment Optical Coherence Tomography: An Updated Review

Yu Jeat Chong^*, Matthew Azzopardi, Gulmeena Hussain, Alberto Recchioni, Jaishree Gandhewar, Constantinos Loizou, Ioannis Giachos, Ankur Barua, Darren S. J. Ting^*

^*Corresponding author for this work

Inflammation and Ageing

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Abstract

Since its introduction, optical coherence tomography (OCT) has revolutionized the field of ophthalmology and has now become an indispensable, noninvasive tool in daily practice. Most ophthalmologists are familiar with its use in the assessment and monitoring of retinal and optic nerve diseases. However, it also has important applications in the assessment of anterior segment structures, including the cornea, conjunctiva, sclera, anterior chamber, and iris, and has the potential to transform the clinical examination of these structures. In this review, we aim to provide a comprehensive overview of the potential clinical utility of anterior segment OCT (AS-OCT) for a wide range of anterior segment pathologies, such as conjunctival neoplasia, pterygium, scleritis, keratoconus, corneal dystrophies, and infectious/noninfectious keratitis. In addition, the clinical applications of AS-OCT (including epithelial mapping) in preoperative planning and postoperative monitoring for corneal and refractive surgeries are discussed.

Original language	English
Article number	122
Journal	Diagnostics
Volume	14
Issue number	2
DOIs	https://doi.org/10.3390/diagnostics14020122
Publication status	Published - 5 Jan 2024

Bibliographical note

D.S.J.T. acknowledges support provided by the Medical Research Council/Fight for Sight Clinical Research Fellowship (MR/T001674/1) and the Fight for Sight/John Lee, Royal College of Ophthalmologists Primer Fellowship (24CO4). A.R. was supported by funding from the IILA-1117-20001 Programme Invention for Innovation (i4i), National Institute for Health and Care Research (NIHR). The views expressed in this article are those of the author(s) and not necessarily those of the NIHR, or the Department of Health and Social Care.

Keywords

keratoconus
optical coherence tomography (OCT)
keratoplasty
keratitis
cornea
epithelial mapping
anterior segment

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ChongYJ2024ClinicalFinal published version, 11.7 MBLicence: Creative Commons: Attribution (CC BY)

Cite this

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title = "Clinical Applications of Anterior Segment Optical Coherence Tomography: An Updated Review",

abstract = "Since its introduction, optical coherence tomography (OCT) has revolutionized the field of ophthalmology and has now become an indispensable, noninvasive tool in daily practice. Most ophthalmologists are familiar with its use in the assessment and monitoring of retinal and optic nerve diseases. However, it also has important applications in the assessment of anterior segment structures, including the cornea, conjunctiva, sclera, anterior chamber, and iris, and has the potential to transform the clinical examination of these structures. In this review, we aim to provide a comprehensive overview of the potential clinical utility of anterior segment OCT (AS-OCT) for a wide range of anterior segment pathologies, such as conjunctival neoplasia, pterygium, scleritis, keratoconus, corneal dystrophies, and infectious/noninfectious keratitis. In addition, the clinical applications of AS-OCT (including epithelial mapping) in preoperative planning and postoperative monitoring for corneal and refractive surgeries are discussed.",

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author = "Chong, {Yu Jeat} and Matthew Azzopardi and Gulmeena Hussain and Alberto Recchioni and Jaishree Gandhewar and Constantinos Loizou and Ioannis Giachos and Ankur Barua and Ting, {Darren S. J.}",

note = "D.S.J.T. acknowledges support provided by the Medical Research Council/Fight for Sight Clinical Research Fellowship (MR/T001674/1) and the Fight for Sight/John Lee, Royal College of Ophthalmologists Primer Fellowship (24CO4). A.R. was supported by funding from the IILA-1117-20001 Programme Invention for Innovation (i4i), National Institute for Health and Care Research (NIHR). The views expressed in this article are those of the author(s) and not necessarily those of the NIHR, or the Department of Health and Social Care.",

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AU - Chong, Yu Jeat

AU - Azzopardi, Matthew

AU - Hussain, Gulmeena

AU - Recchioni, Alberto

AU - Gandhewar, Jaishree

AU - Loizou, Constantinos

AU - Giachos, Ioannis

AU - Barua, Ankur

AU - Ting, Darren S. J.

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N2 - Since its introduction, optical coherence tomography (OCT) has revolutionized the field of ophthalmology and has now become an indispensable, noninvasive tool in daily practice. Most ophthalmologists are familiar with its use in the assessment and monitoring of retinal and optic nerve diseases. However, it also has important applications in the assessment of anterior segment structures, including the cornea, conjunctiva, sclera, anterior chamber, and iris, and has the potential to transform the clinical examination of these structures. In this review, we aim to provide a comprehensive overview of the potential clinical utility of anterior segment OCT (AS-OCT) for a wide range of anterior segment pathologies, such as conjunctival neoplasia, pterygium, scleritis, keratoconus, corneal dystrophies, and infectious/noninfectious keratitis. In addition, the clinical applications of AS-OCT (including epithelial mapping) in preoperative planning and postoperative monitoring for corneal and refractive surgeries are discussed.

AB - Since its introduction, optical coherence tomography (OCT) has revolutionized the field of ophthalmology and has now become an indispensable, noninvasive tool in daily practice. Most ophthalmologists are familiar with its use in the assessment and monitoring of retinal and optic nerve diseases. However, it also has important applications in the assessment of anterior segment structures, including the cornea, conjunctiva, sclera, anterior chamber, and iris, and has the potential to transform the clinical examination of these structures. In this review, we aim to provide a comprehensive overview of the potential clinical utility of anterior segment OCT (AS-OCT) for a wide range of anterior segment pathologies, such as conjunctival neoplasia, pterygium, scleritis, keratoconus, corneal dystrophies, and infectious/noninfectious keratitis. In addition, the clinical applications of AS-OCT (including epithelial mapping) in preoperative planning and postoperative monitoring for corneal and refractive surgeries are discussed.

KW - keratoconus

KW - optical coherence tomography (OCT)

KW - keratoplasty

KW - keratitis

KW - cornea

KW - epithelial mapping

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SN - 2075-4418

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JO - Diagnostics

JF - Diagnostics

IS - 2

M1 - 122

ER -

Clinical Applications of Anterior Segment Optical Coherence Tomography: An Updated Review

Abstract

Bibliographical note

Keywords

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