Challenges of biomolecular detection at the nanoscale: nanopores and microelectrodes

K. Mathwig, T. Albrecht, E.D. Goluch, L. Rassaei

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)


The interest in analytical devices, which typically rely on the reactivity of a biological component for specificity, is growing rapidly. In this Perspective, we highlight current challenges in all-electrical biosensing as these systems shrink toward the nanoscale and enable the detection of analytes at the single-molecule level. We focus on two sensing principles: nanopores and amperometric microelectrode devices.
Original languageEnglish
Pages (from-to)5470-5475
Number of pages6
JournalAnalytical Chemistry
Issue number11
Early online date13 May 2015
Publication statusPublished - 2 Jun 2015

Cite this