Abstract
This work aims to show the possibility to perform in-vivo acquisitions with high sampling rate (20 Hz) with Time Domain functional Near-Infrared Spectroscopy (TD fNIRS) for studying brain resting state oscillations. Based on numerical simulations, a protocol was designed for acquiring hemodynamics parameters on 13 healthy volunteers during normal and forced respiration. Both the experiments had a length of 15 minutes and during the forced respiration one, subjects were ask to breath at 5 breaths per minute (0.083 Hz) following a metronome. Systemic (UP) and cortical (DW) oxy- (O2Hb) and deoxy- (HHb) hemoglobin concentrations (absolute values) were successfully retrieved with a single measure on the frontal lobe. Temporal series and Power Spectral Density (PSD) were calculated for: physiological signals (electrocardiogram, breath signal, blood volume pulse, skin conductance and temperature), total counts at the two wavelengths (RED = 689.5±0.5 nm and IR=828.5±0.5 nm), counts in temporal gates for RED and IR, absolute values of O2Hb_UP, O2Hb_DW, HHb_UP and HHb_DW. Specific characteristic peaks were evaluated in the cardiac, respiratory, low, and very low frequency bands. The behavior among the subjects was uniform and differences between the two experiments were found.
Original language | English |
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Title of host publication | Diffuse Optical Spectroscopy and Imaging IX |
Editors | Davide Contini, Yoko Hoshi, Thomas D. O'Sullivan |
Publisher | SPIE |
ISBN (Electronic) | 9781510664661 |
ISBN (Print) | 9781510664654 |
DOIs | |
Publication status | Published - 9 Aug 2023 |
Event | Diffuse Optical Spectroscopy and Imaging IX 2023 - Munich, Germany Duration: 25 Jun 2023 → 28 Jun 2023 |
Publication series
Name | Proceedings of SPIE - The International Society for Optical Engineering |
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Volume | 12628 |
ISSN (Print) | 0277-786X |
ISSN (Electronic) | 1996-756X |
Conference
Conference | Diffuse Optical Spectroscopy and Imaging IX 2023 |
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Country/Territory | Germany |
City | Munich |
Period | 25/06/23 → 28/06/23 |
Bibliographical note
Funding Information:This work was supported by the Laserlab-Europe EU-H2020 871124 project.
Publisher Copyright:
© 2023 SPIE.
Keywords
- brain
- resting state oscillations
- Time domain near infrared spectroscopy
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering