Carbamazepine-induced acute liver failure as part of the DRESS syndrome.

WK Syn, DJ Naisbitt, Andrew Holt, M Pirmohamed, David Mutimer

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47 Citations (Scopus)


Carbamazepine is a widely used drug. It is commonly associated with hepatic abnormalities, ranging from an asymptomatic rise in liver function tests to acute liver failure. The most severe reaction occurs as part of a generalised hypersensitivity reaction, also known as drug reaction, eosinophilia and systemic symptoms (DRESS). We describe a case of a young adult who presented with non-specific symptoms, which progressed to fulminant hepatic failure, displaying the hallmarks of DRESS. We highlight the need for awareness of such an association.
Original languageEnglish
Pages (from-to)988-91
Number of pages4
JournalInternational Journal of Clinical Practice
Issue number8
Publication statusPublished - 1 Aug 2005


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