TY - JOUR
T1 - Carbamazepine-induced acute liver failure as part of the DRESS syndrome.
AU - Syn, WK
AU - Naisbitt, DJ
AU - Holt, Andrew
AU - Pirmohamed, M
AU - Mutimer, David
PY - 2005/8/1
Y1 - 2005/8/1
N2 - Carbamazepine is a widely used drug. It is commonly associated with hepatic abnormalities, ranging from an asymptomatic rise in liver function tests to acute liver failure. The most severe reaction occurs as part of a generalised hypersensitivity reaction, also known as drug reaction, eosinophilia and systemic symptoms (DRESS). We describe a case of a young adult who presented with non-specific symptoms, which progressed to fulminant hepatic failure, displaying the hallmarks of DRESS. We highlight the need for awareness of such an association.
AB - Carbamazepine is a widely used drug. It is commonly associated with hepatic abnormalities, ranging from an asymptomatic rise in liver function tests to acute liver failure. The most severe reaction occurs as part of a generalised hypersensitivity reaction, also known as drug reaction, eosinophilia and systemic symptoms (DRESS). We describe a case of a young adult who presented with non-specific symptoms, which progressed to fulminant hepatic failure, displaying the hallmarks of DRESS. We highlight the need for awareness of such an association.
U2 - 10.1111/j.1368-5031.2005.00550.x
DO - 10.1111/j.1368-5031.2005.00550.x
M3 - Article
C2 - 16033627
SN - 1742-1241
VL - 59
SP - 988
EP - 991
JO - International Journal of Clinical Practice
JF - International Journal of Clinical Practice
IS - 8
ER -