Can tactile reactivity in preterm born infants be explained by an immature cortical response to tactile stimulation in the first year? A pilot study

Ana Carolina Cabral de Paula Machado; Lívia de Castro Magalhães; Suelen Rosa de Oliveira; Sérgio Luiz Novi; Rickson C. Mesquita; Débora Marques de Miranda; Maria Cândida F. Bouzada

doi:10.1038/s41372-022-01536-w

Can tactile reactivity in preterm born infants be explained by an immature cortical response to tactile stimulation in the first year? A pilot study

Ana Carolina Cabral de Paula Machado^*, Lívia de Castro Magalhães, Suelen Rosa de Oliveira, Sérgio Luiz Novi, Rickson C. Mesquita, Débora Marques de Miranda, Maria Cândida F. Bouzada

^*Corresponding author for this work

Computer Science

Research output: Contribution to journal › Article › peer-review

Abstract

This study aimed to compare preterm (PT) and full-term (FT) infants’ adaptive behavior and functional cortical response to tactile stimulus, as measured by Test of Sensory Functions in Infants and functional Near-Infrared Spectroscopy (fNIRS). Outcome measures were taken at 6 (PT = 26/FT = 21 infants) and 12 months (PT = 15/FT = 14 infants). At 6 months, poorer tactile reactivity was observed in PT, but not confirmed at 12 months. At 6 months, cortical response to tactile stimulus was found in the primary sensorimotor cortex and differences between groups did not reach significance. At 12 months, cortical response was found in the primary sensorimotor cortex and premotor area and in the somatosensory associative area, with significant less frequent response in premotor area in PT. The findings reinforce fNIRS as a tool to complement the knowledge of tactile adaptive behaviors in PT in early life.

Original language	English
Pages (from-to)	728-734
Number of pages	7
Journal	Journal of Perinatology
Volume	43
Issue number	6
Early online date	19 Oct 2022
DOIs	https://doi.org/10.1038/s41372-022-01536-w
Publication status	Published - Jun 2023

Bibliographical note

Funding Information:
We thank the infants and families who participated in our study and all the professionals of the multidisciplinary follow-up program of risk infants in the Federal University of Minas Gerais’ Clinical Hospital (ACRIAR). This study received funding from the Minas Gerais Research Foundation – FAPEMIG (grant number APQ-01182-13), the São Paulo Research Foundation – FAPESP (great number 2012/02500-8 and 2013/07559-3) and the National Council for Scientific and Technological Development (CNPq) - Brazil (grant number 140675/2017-5).

Publisher Copyright:
© 2022, The Author(s), under exclusive licence to Springer Nature America, Inc.

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynaecology

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10.1038/s41372-022-01536-w

Cite this

Machado, A. C. C. D. P., Magalhães, L. D. C., de Oliveira, S. R., Novi, S. L., Mesquita, R. C., de Miranda, D. M., & Bouzada, M. C. F. (2023). Can tactile reactivity in preterm born infants be explained by an immature cortical response to tactile stimulation in the first year? A pilot study. Journal of Perinatology, 43(6), 728-734. https://doi.org/10.1038/s41372-022-01536-w

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abstract = "This study aimed to compare preterm (PT) and full-term (FT) infants{\textquoteright} adaptive behavior and functional cortical response to tactile stimulus, as measured by Test of Sensory Functions in Infants and functional Near-Infrared Spectroscopy (fNIRS). Outcome measures were taken at 6 (PT = 26/FT = 21 infants) and 12 months (PT = 15/FT = 14 infants). At 6 months, poorer tactile reactivity was observed in PT, but not confirmed at 12 months. At 6 months, cortical response to tactile stimulus was found in the primary sensorimotor cortex and differences between groups did not reach significance. At 12 months, cortical response was found in the primary sensorimotor cortex and premotor area and in the somatosensory associative area, with significant less frequent response in premotor area in PT. The findings reinforce fNIRS as a tool to complement the knowledge of tactile adaptive behaviors in PT in early life.",

author = "Machado, {Ana Carolina Cabral de Paula} and Magalh{\~a}es, {L{\'i}via de Castro} and {de Oliveira}, {Suelen Rosa} and Novi, {S{\'e}rgio Luiz} and Mesquita, {Rickson C.} and {de Miranda}, {D{\'e}bora Marques} and Bouzada, {Maria C{\^a}ndida F.}",

note = "Funding Information: We thank the infants and families who participated in our study and all the professionals of the multidisciplinary follow-up program of risk infants in the Federal University of Minas Gerais{\textquoteright} Clinical Hospital (ACRIAR). This study received funding from the Minas Gerais Research Foundation – FAPEMIG (grant number APQ-01182-13), the S{\~a}o Paulo Research Foundation – FAPESP (great number 2012/02500-8 and 2013/07559-3) and the National Council for Scientific and Technological Development (CNPq) - Brazil (grant number 140675/2017-5). Publisher Copyright: {\textcopyright} 2022, The Author(s), under exclusive licence to Springer Nature America, Inc.",

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Can tactile reactivity in preterm born infants be explained by an immature cortical response to tactile stimulation in the first year? A pilot study. / Machado, Ana Carolina Cabral de Paula; Magalhães, Lívia de Castro; de Oliveira, Suelen Rosa et al.
In: Journal of Perinatology, Vol. 43, No. 6, 06.2023, p. 728-734.

Research output: Contribution to journal › Article › peer-review

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AU - Mesquita, Rickson C.

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AU - Bouzada, Maria Cândida F.

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Can tactile reactivity in preterm born infants be explained by an immature cortical response to tactile stimulation in the first year? A pilot study

Abstract

Bibliographical note

ASJC Scopus subject areas

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