Building mouse phenotype ontologies.

G V Gkoutos, E C J Green, a M Mallon, J M Hancock, D Davidson

Research output: Contribution to journalArticlepeer-review

38 Citations (Scopus)

Abstract

The structured description of mutant phenotypes presents a major conceptual and practical problem. A general model for generating mouse phenotype ontologies that involves combing a variety of different ontologies to better link and describe phenotypes is presented. This model is based on the Phenotype and Trait Ontology schema proposal and incorporates practical limitations and designing solutions in an attempt to model a testbed for the first phenotype ontology constructed in this manner, namely the mouse behavior phenotype ontology. We propose the application of such a model could provide curators with a powerful mechanism of annotation, mining and knowledge representation as well as achieving some level of free text disassociation.
Original languageEnglish
Pages (from-to)178-189
Number of pages12
JournalPacific Symposium on Biocomputing. Proceedings.
Volume189
Publication statusPublished - 2004

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