TY - UNPB
T1 - Applications Of Stem Cell-Derived Extracellular Vesicles in Nerve Regeneration
AU - Yavuz, Burcak
AU - Mutlu, Esra
AU - Ahmed, Zubair
AU - Ben-Nissan, Besim
AU - Stamboulis, Artemis
PY - 2023/10/10
Y1 - 2023/10/10
N2 - Extracellular vesicles (EVs), including exosomes, microvesicles, and other lipid vesicles derived from cells, play a pivotal role in intercellular communication by transferring information between cells. EVs secreted by progenitor and stem cells have been associated with the therapeutic effects observed in cell-based therapies, and they also contribute to tissue regeneration following injury, such as in orthopedic surgery cases. This review briefly explores the involvement of EVs in tissue repair and nerve regeneration, their potential as drug carriers, and their significance in stem cell research and cell-based therapies. It underscores the importance for bioengineers to comprehend and manipulate EV activity to optimize the efficacy of tissue engineering and regenerative therapies.
AB - Extracellular vesicles (EVs), including exosomes, microvesicles, and other lipid vesicles derived from cells, play a pivotal role in intercellular communication by transferring information between cells. EVs secreted by progenitor and stem cells have been associated with the therapeutic effects observed in cell-based therapies, and they also contribute to tissue regeneration following injury, such as in orthopedic surgery cases. This review briefly explores the involvement of EVs in tissue repair and nerve regeneration, their potential as drug carriers, and their significance in stem cell research and cell-based therapies. It underscores the importance for bioengineers to comprehend and manipulate EV activity to optimize the efficacy of tissue engineering and regenerative therapies.
KW - nerve regeneration
KW - non-coding RNAs
KW - exosome
KW - traumatic brain injury
KW - blood-brain barrier
U2 - 10.20944/preprints202310.0557.v1
DO - 10.20944/preprints202310.0557.v1
M3 - Preprint
BT - Applications Of Stem Cell-Derived Extracellular Vesicles in Nerve Regeneration
PB - MDPI
ER -