Acute myeloid leukaemia presenting as cholestatic hepatitis

Farooq Wandroo, James Murray, David Mutimer, Stefan Hubscher

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

A 40 year old man presented with abdominal pain, jaundice, weight loss, and hepatosplenomegaly. Liver function tests revealed cholestatic jaundice and a computed tomography scan showed an enlarged liver, with a normal biliary tree. Liver biopsy showed diffuse infiltration by neutrophils, monocytoid cells, and blasts. Peripheral blood film and bone marrow were consistent with acute myeloid leukaemia. After treatment with chemotherapy using an acute myeloid leukaemia protocol (UK Medical Research Council AML-12), there was complete resolution of jaundice and the patient went into complete molecular remission.
Original languageEnglish
Pages (from-to)544-545
Number of pages2
JournalJournal of Clinical Pathology
Volume57(5)
Issue numberMay
Publication statusPublished - 1 Jan 2004

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