Abstract
The posttranslational modification of histones by acetylation or methylation regulates chromatin structure and can determine how a DNA sequence is interpreted by, for example, the transcriptional machinery. In this issue of Cell, Pokholok and colleagues (2005) describe a new and reliable genome-wide microarray study of histone modifications and gene expression in yeast. Their epigenetic map can be used to guide further research on the epigenome.
Original language | English |
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Pages (from-to) | 489-491 |
Number of pages | 3 |
Journal | Cell |
Volume | 122 |
DOIs | |
Publication status | Published - 26 Aug 2005 |