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Towards a Single-Molecule Pharmacology of G-Protein-Coupled Receptors: Understanding Receptor Dynamics to Develop Innovative Drugs
Calebiro, Davide
(Principal Investigator)
Metabolism and Systems Research
Overview
Fingerprint
Research output
(2)
Project Details
Short title
Towards a Single-Molecule Pharmacology of G-Protein-Coupled Receptors: Understanding Receptor Dynamics to Develop Innovative Drugs
Status
Active
Effective start/end date
12/03/19
→
12/03/24
Funding
THE WELLCOME TRUST
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Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
metabotropic glutamate receptor 4
Medicine & Life Sciences
100%
Metabotropic Glutamate Receptors
Medicine & Life Sciences
74%
trajectories
Physics & Astronomy
46%
trapping
Physics & Astronomy
45%
Synaptic Transmission
Medicine & Life Sciences
41%
particle trajectories
Physics & Astronomy
35%
adrenergics
Physics & Astronomy
24%
voltage-dependent calcium channel (P-Q type)
Medicine & Life Sciences
24%
Research output
Research output per year
2020
2020
2021
2021
2
Article
Research output per year
Research output per year
Detecting transient trapping from a single trajectory: a structural approach
Lanoiselee, Y.
,
Grimes, J.
,
Koszegi, Z.
&
Calebiro, D.
,
13 Aug 2021
,
In:
Entropy.
23
,
8
,
16 p.
, 1044.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
trajectories
100%
trapping
97%
particle trajectories
75%
adrenergics
52%
stimulation
31%
34
Downloads (Pure)
Super-resolution imaging reveals the nanoscale organization of metabotropic glutamate receptors at presynaptic active zones
Siddig, S.
,
Aufmkolk, S.
,
Doose, S.
,
Jobin, M-L.
,
Werner, C.
,
Sauer, M.
&
Calebiro, D.
,
15 Apr 2020
,
In:
Science Advances.
6
,
16
,
12 p.
, eaay7193.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
metabotropic glutamate receptor 4
100%
Metabotropic Glutamate Receptors
74%
Synaptic Transmission
41%
voltage-dependent calcium channel (P-Q type)
24%
Cerebellum
13%
13
Citations (Scopus)
103
Downloads (Pure)