Proposal for a collaborative research project to investigate the mechanisms of metabolic escape of SDHB Defective Tumours

Tennant, Daniel (Principal Investigator)

Metabolism and Systems Research

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2015
Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism
Lussey-Lepoutre, C., Hollinshead, K., Ludwig, C., Menara, M., Morin, A., Castro-Vega, L-J., Parker, S. J., Janin, M., Martinelli, C., Ottolenghi, C., Metallo, C., Gimenez-Roqueplo, A-P., Favier, J. & Tennant, D., 2 Nov 2015, In: Nature Communications. 6, 8784.
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