Prem Kumar

Research output

Research output per year 1988 2001 2006 2007 2023

• 63 Article
• 32 Abstract
• 6 Chapter
• 2 Chapter (peer-reviewed)
• 8 More
  • 2 Paper
  • 2 Review article
  • 1 Conference contribution
  • 1 Comment/debate
  • 1 Editorial
  • 1 Letter

Research output per year

Research output per year

Search results

• 2007

  Calcium oscillations induced by ATP in human umbilical cord smooth muscle cells

  Meng, F., To, W., Kirkman-Brown, J., Kumar, P. & Gu, Y., 1 Oct 2007, In: Journal of Cellular Physiology. 213, 1, p. 79-87 9 p.

  Research output: Contribution to journal › Article

  • Calcium Signaling 100%
  • Umbilical Cord 96%
  • Smooth Muscle Myocytes 74%
  • Adenosine Triphosphate 65%
  • alpha,beta-methyleneadenosine 5'-triphosphate 42%
  12 Citations (Scopus)

• How sweet it is: sensing low glucose in the carotid body

  Kumar, P., 1 Feb 2007, In: The Journal of Physiology. 578, p. 627 1 p.

  Research output: Contribution to journal › Article
  16 Citations (Scopus)

• Respiratory chemoreceptor function in vertebrates comparative and evolutionary aspects

  Sundin, L., Burleson, M. L., Sanchez, A. P., Amin-Naves, J., Kinkead, R., Gargaglioni, L. H., Hartzler, L. K., Wiemann, M., Kumar, P. & Glass, M. L., Oct 2007, In: Integrative and Comparative Biology. 47, 4, p. 592-600 9 p.

  Research output: Contribution to journal › Article › peer-review

  • chemoreceptors 100%
  • vertebrates 62%
  • carbon dioxide 42%
  • breathing 34%
  • lung function 34%
  20 Citations (Scopus)

• Sensing hypoxia: Carotid body mechanisms and reflexes in health and disease - Foreword

  Kumar, P. & Prabhakar, N., 1 Jul 2007, In: Respiratory physiology & neurobiology. 157, 1, p. 1-3 3 p.

  Research output: Contribution to journal › Editorial
  17 Citations (Scopus)

• Sensing hypoxia in the carotid body: from stimulus to response.

  Kumar, P., 1 Jan 2007, In: Essays in Biochemistry. 43, p. 43-60 18 p.

  Research output: Contribution to journal › Article

  • Carotid Body 100%
  • PO-2 73%
  • Hypoxia 58%
  • Oxygen 42%
  • Hyperoxia 36%
  36 Citations (Scopus)

• Translating blood-borne stimuli: chemotransduction in the carotid body

  Kumar, P., 1 Jan 2007, In: Acta Physiologica Sinica. In Press, p. 128-32 5 p.

  Research output: Contribution to journal › Article

  • Carotid Body 100%
  • Hypoxia 58%
  • Cell Body 24%
  • Neurosecretion 19%
  • AMP-Activated Protein Kinases 14%
• 2006

  Adrenaline increases carotid body CO2 sensitivity: An in vivo study

  Maskell, PD., Rusius, CJ., Whitehead, K. & Kumar, P., 1 Jan 2006, p. 245-250. 6 p.

  Research output: Contribution to conference (unpublished) › Paper

  8 Citations (Scopus)

• AMP activated protein kinase: Function and dysfunction in health and disease

  Kumar, P. & Peers, C., 16 Feb 2006, In: The Journal of Physiology. 574, p. 3-6 4 p.

  Research output: Contribution to journal › Article
  5 Citations (Scopus)

• AMP-activated protein kinase couples mitochondrial inhibition by hypoxia to cell specific Ca2+ signaling mechanisms in oxygen-sensing cells

  Evans, AM., Hardie, DG., Galione, A., Peers, C., Kumar, P. & Wyatt, CN., 1 Jan 2006, Signalling pathways in Acute Oxygen Sensing. Novartis Foundation Symposium.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• A role for TRP channels in carotid body chemotransduction

  Kumar, P., Pearson, SA. & Gu, Y., 1 Jan 2006, p. A1229.

  Research output: Contribution to conference (unpublished) › Abstract

• A role for TRPC in chemotransduction?

  Pearson, SA., Gu, Y. & Kumar, P., 1 Jan 2006, p. 32. 1 p.

  Research output: Contribution to conference (unpublished) › Abstract

• Calcium oscillations induced by ATP in human umbilical cord smooth muscle cells

  Gu, Y., Zhang, O., Meng, O. & Kumar, P., 1 Jan 2006, p. A1175.

  Research output: Contribution to conference (unpublished) › Abstract

• Direct Inhibition of TRPC3 by polyunsaturated fatty acids in MCF-7 breast cancer cells

  Gu, Y., To, O., Kirkman-Brown, O., Zhang, O., Potier, O., Vandier, O. & Kumar, P., 1 Jan 2006, p. A329.

  Research output: Contribution to conference (unpublished) › Abstract

• Does AMP-activated protein kinase couple hypoxic inhibition of oxidative phosphorylation to carotid body excitation?

  Wyatt, CN., Kumar, P., Aley, P., Peers, C., Hardie, DG. & Evans, AM., 1 Jan 2006, p. 191-196. 6 p.

  Research output: Contribution to conference (unpublished) › Paper

  7 Citations (Scopus)

• Insulin induced hyperpnea: a model for exercise?

  Kumar, P., Maskell, P. & Bin-Jaliah, I., 1 Jan 2006, p. 92. 1 p.

  Research output: Contribution to conference (unpublished) › Abstract

• Oxygen sensing mechanism of the carotid body

  Kumar, P., 1 Jan 2006, p. PL5, pg 6.

  Research output: Contribution to conference (unpublished) › Abstract

• The effect of AMP-kinase activators on oxygen-sensing type-I cells of the rat carotid body

  Wyatt, CN., Peers, C., Kumar, P., Hardie, DG. & Evans, AM., 1 Jan 2006, p. 049P.

  Research output: Contribution to conference (unpublished) › Abstract

• Vasoconstrictor responses in rat femoral artery: effects of early chronic systemic hypoxia

  Mukerji, S., Kumar, P. & Coney, A., 1 Jan 2006, p. C61.

  Research output: Contribution to conference (unpublished) › Abstract
• 2005

  Carbon dioxide sensitivity during hypoglycaemia-induced, elevated metabolism in the anaesthetized rat

  Bin-Jaliah, I., Maskell, P. & Kumar, P., 15 Mar 2005, In: The Journal of Physiology. 563, 3, p. 883-893 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Carbon Dioxide 100%
  • Carbon Monoxide 96%
  • Hypoglycemia 91%
  • Carotid Body 51%
  • Insulin 38%
  25 Citations (Scopus)

• Chronic hypoxia enhances calcium handling in human pulmonary artery smooth muscle cells

  Gu, Y., Montgomery, L. & Kumar, P., 1 Jan 2005, In: Proceedings of The Physiological Society. 567P, p. PC103

  Research output: Contribution to journal › Abstract

• Does AMP-activated protein kinase couple inhibition of mitochondrial oxidative phosphorylation by hypoxia to calcium signaling in O2-sensing cells?

  Evans, AM., Mustard, K., Wyatt, CJ., Peers, C., Dipp, M., Kumar, P. & Kinnear, NP., 17 Oct 2005, In: Journal of Biological Chemistry. 280, p. 41504-41511 8 p.

  Research output: Contribution to journal › Article

  • AMP-Activated Protein Kinases 100%
  • Calcium Signaling 98%
  • Oxidative Phosphorylation 94%
  • Psychological Inhibition 68%
  • Hypoxia 65%
  150 Citations (Scopus)

• Does chemoreceptor gain increase during hypermetabolism?

  Maskell, P., Bin-Jaliah, I., Rusius, CJ., Whitehead, K. & Kumar, P., 1 Jan 2005, p. 369. 1 p.

  Research output: Contribution to conference (unpublished) › Abstract

• Making sense of the carotid body

  Kumar, P., 1 Jan 2005, In: Journal of Comparative Physiology A. 141A, p. S96

  Research output: Contribution to journal › Abstract
• 2004

  Acidosis abolishes the effect of repeated applications of ATP on pulmonary artery force and [Ca2+]i

  Dubuis, E., Kumar, P., Gautier, M., Girardin, C. & Vandier, C., 1 Jul 2004, In: Respiratory physiology & neurobiology. 141, p. 157-166 10 p.

  Research output: Contribution to journal › Article

  • Acidosis 100%
  • Pulmonary Artery 88%
  • Adenosine Triphosphate 75%
  • Smooth Muscle 21%
  • Purine Nucleotides 17%
  1 Citation (Scopus)

• Carbon-monoxide induced alterations in expression of Kca channels in pulmonary artery smooth muscle cells

  Wang, R., Dubuis, E., Kumar, P., Bonnet, P. & Vandier, C., 1 Jan 2004, Signal Transduction and the Gasotransmitters.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Hypoglycaemia-evoked hypermetabolism increases peripheral chemoreceptor gain in anaesthetised rats

  Bin-Jaliah, I., Maskell, P. & Kumar, P., 1 Jan 2004, In: The Journal of Physiology. 560P, p. PC5

  Research output: Contribution to journal › Abstract

• Indirect sensing of insulin-induced hypoglycaemia by the carotid body in the rat

  Bin-Jaliah, I., Maskell, P. D. & Kumar, P., 1 Apr 2004, In: The Journal of Physiology. 556, 1, p. 255-66 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Carotid Body 100%
  • Hypoglycemia 71%
  • Carbon Monoxide 56%
  • Insulin 50%
  • Ventilation 49%
  64 Citations (Scopus)

• The potential role for AMP-kinase in hypoxic chemotransduction of rat carotid body

  Wyatt, CN., Kumar, P., Peers, C., Kang, P., Hardie, DG. & Evans, AM., 1 Jan 2004, In: The Journal of Physiology. 560P, p. C44

  Research output: Contribution to journal › Abstract
• 2003

  External acidosis abolishes the difference in response to ATP between large and small rat pulmonary artery smooth muscle cells

  Dubuis, E., Kumar, P., Gautier, M., Girardin, C., Bonnet, P. & Vandier, C., 1 Jan 2003, In: The Journal of Physiology. 548P, p. C24

  Research output: Contribution to journal › Abstract

• Low glucose and carotid body-mediated CO2 chemosensitivity in the rat

  Bin-Jaliah, I., Maskell, P. & Kumar, P., 1 Jan 2003, In: The Journal of Physiology. 552P, p. C47

  Research output: Contribution to journal › Abstract

• Regulation of K+ currents by CO in carotid body Type I cells and pulmonary artery smooth muscle cells

  Pequignot, J-M., Gonzalez, C., Nurse, CA., Prabhakar, NR., Dalmaz, Y., Kumar, P., Dubuis, E. & Vandier, C., 1 Jan 2003, Chemoreception: From cellular signalling to functional plasticity.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Regulation of K+ currents by CO in carotid body Type I cells and pulmonary artery smooth muscle cells

  Kumar, P., Dubuis, E. & Vandier, C., 1 Jan 2003, In: Advances in Experimental Medicine and Biology. 536, p. 147-154 8 p.

  Research output: Contribution to journal › Article

• The carotid body-mediated ventilatory response to insulin-induced hypoglycaemia in anaesthetized rats

  Bin-Jaliah, I. & Kumar, P., 1 Jan 2003, In: The Journal of Physiology. 551P, p. C44

  Research output: Contribution to journal › Abstract
• 2002

  A dual site of action for hypoxia in the mammalian carotid body?

  Kumar, P., 1 Jan 2002, In: Journal of Comparative Physiology A. 132/A, p. S25

  Research output: Contribution to journal › Abstract

• A possible dual site of action for carbon monoxide-mediated chemoexcitation in the rat carotid body

  Barbe, C., Al Hashem, F., Conway, A., Dubuis, E., Vandier, C. & Kumar, P., 15 Sept 2002, In: The Journal of Physiology. 543.3, p. 933-945 13 p.

  Research output: Contribution to journal › Article

  • Carotid Body 100%
  • Carbon Monoxide 75%
  • Patch-Clamp Techniques 17%
  • Membrane Potentials 16%
  • Purinergic Antagonists 13%
  24 Citations (Scopus)

• Maturation of chemoreceptor O2 and CO2 sensitivity

  Kumar, P., Lahiri, S., Semenza, G. & Prabhakar, NR., 1 Jan 2002, Oxygen Sensing: Responses and Adaptations to Hypoxia.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
• 2001

  Chemoreceptors

  Kumar, P., 1 Jan 2001, The Oxford Companion to the Body.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Effect of carbon monoxide on whole-cell currents of the isolated rat carotid body type I cell

  Barbe, C., Dubuis, E., Vandier, C. & Kumar, P., 1 Jan 2001, In: The Journal of Physiology. 533P, p. 108-109 2 p.

  Research output: Contribution to journal › Abstract

• Effect of monoxide upon adult and neonatal carotid bodies in vitro

  Kumar, P., Al-Hashem, F. & Barbe, C., 1 Jan 2001, In: FASEB Journal. 15, p. A817

  Research output: Contribution to journal › Abstract

• Interaction of ATP and CO2 upon carotid body chemosensitivity in vitro

  Al-Hashem, F., Barbe, C. & Kumar, P., 1 Jan 2001, In: The Journal of Physiology. 536P, p. 142P

  Research output: Contribution to journal › Abstract

• Postnatal maturation of peripheral chemosensitivity: from reflexes to mechanisms

  Kumar, P., 1 Jan 2001, In: The Journal of Physiology. 533P, p. 12S

  Research output: Contribution to journal › Abstract

• Purinergic modulation of peripheral CO2 ventilatory chemosensitivity

  Al-Hashem, F. & Kumar, P., 1 Jan 2001, In: The Journal of Physiology. 531P, p. 96-97P

  Research output: Contribution to journal › Abstract
• 2000

  Effect of adenosine on CO2 chemosensitivity. Functional, cellular, and molecular studies

  Kumar, P., Conway, A. F., Vandier, C., Marshall, N. J., Bruynseels, J. & Matthews, G. M., 2000, In: Advances in Experimental Medicine and Biology. 475, p. 405-10 6 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)
• 1999

  Presynaptic action of adenosine on a 4-aminopyridine-sensitive current in the rat carotid body

  Vandier, C., Conway, A. F., Landauer, R. C. & Kumar, P., 1 Mar 1999, In: The Journal of Physiology. 515 ( Pt 2), p. 419-29 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Carotid Body 100%
  • 4-Aminopyridine 95%
  • Adenosine 72%
  • Gallopamil 19%
  • Membrane Potentials 13%
  40 Citations (Scopus)
• 1997

  A more cultured approach to peripheral chemotransduction

  Kumar, P., 15 Sept 1997, In: The Journal of Physiology. 503 ( Pt 3), p. 470

  Research output: Contribution to journal › Article › peer-review
• 1996

  Extracellular potassium and chemosensitivity in the rat carotid body, in vitro

  Pepper, D. R., Landauer, R. C. & Kumar, P., 15 Jun 1996, In: The Journal of Physiology. 493 ( Pt 3), p. 833-43 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Carotid Body 100%
  • Hyperoxia 92%
  • Potassium 66%
  • Hypoxia 58%
  • Architectural Accessibility 44%
  11 Citations (Scopus)

• Modifications of carotid body CO2 chemosensitivity in vitro

  Kumar, P., Landauer, R. C. & Pepper, D. R., 1996, In: Advances in Experimental Medicine and Biology. 410, p. 203-10 8 p.

  Research output: Contribution to journal › Article › peer-review

• Postnatal development of the pattern of respiratory and cardiovascular response to systemic hypoxia in the piglet: the roles of adenosine

  Elnazir, B., Marshall, J. M. & Kumar, P., 15 Apr 1996, In: The Journal of Physiology. 492 ( Pt 2), p. 573-85 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Adenosine 100%
  • Vasoconstriction 90%
  • Thigh 82%
  • Hypoxia 80%
  • Kidney 54%
  44 Citations (Scopus)
• 1995

  Effect of chronic hypoxaemia from birth upon chemosensitivity in the adult rat carotid body in vitro

  Landauer, R. C., Pepper, D. R. & Kumar, P., 1 Jun 1995, In: The Journal of Physiology. 485 ( Pt 2), p. 543-50 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Carotid Body 100%
  • Hypoxia 58%
  • Parturition 51%
  • In Vitro Techniques 32%
  • Architectural Accessibility 29%
  29 Citations (Scopus)

• Postnatal development of CO2-O2 interaction in the rat carotid body in vitro

  Pepper, D. R., Landauer, R. C. & Kumar, P., 1 Jun 1995, In: The Journal of Physiology. 485 ( Pt 2), p. 531-41 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Carotid Body 100%
  • In Vitro Techniques 32%
  • Regression Analysis 24%
  • Hyperoxia 23%
  • Hypoxia 14%
  82 Citations (Scopus)