Harriet Giddings

I am currently a PhD student at the University of Birmingham, based in the Institute of Microbiology and Infection (IMI). My research aims to decipher the role of Helicobacter pylori in the development of gastric adenocarcinoma (stomach cancer) and whether particular bacterial virulence factors are a driving force in this pathogenesis. To study H. pylori infection in vitro, I use 2D and 3D primary gastric organoid models which are derived from patient biopsy tissue. In addition to 2D and 3D cell culture, I am experienced in fluorescence microscopy , molecular microbiology (such as qPCR to study infection response) and culture of fastidious microorganisms.

I have a strong background in microbiology and hold an MSc (by research) in oral and dental science from The University of Bristol, where my project identified the role of Streptococcal surface proteins in the development of infective endocarditis using molecular microbiology and proteomic data analysis. 

In addition, I am a postgraduate demonstrator for the School of Bioscience, assisting in laboratory practicals, seminars and workshops for years 1, 2 and 3 students across the college. I have also assisted in supervising Masters and PhD students within the laboratory.

I am passionate about making science accessible and easy to understand for everyone; and alongside my supervisor I have hosted college students for work experience placements within the IMI.