%PDF-1.3
%
1 0 obj
<<
/Names 2 0 R
/Type /Catalog
/Outlines 3 0 R
/AcroForm 4 0 R
/OutputIntents [5 0 R 6 0 R]
/Metadata 7 0 R
/PageMode /UseOutlines
/Pages 8 0 R
>>
endobj
9 0 obj
<<
/Producer <4163726F6261742044697374696C6C65722031302E312E35202857696E646F7773293B206D6F646966696564207573696E67206954657874AE20352E332E3520A9323030302D32303132203154335854204256424120284147504C2D76657273696F6E29>
/CrossmarkMajorVersionDate (2015-11-19)
/Keywords (Children,Central nervous system tumours,High-dose chemotherapy,Haematopoietic stem cell transplantation,Systematic review)
/CrossMarkDomains#5B1#5D (springer.com)
/ModDate (D:20151120134522+01'00')
/Subject (Systematic Reviews, 2015, doi:10.1186/s13643-015-0155-7)
/Creator (Arbortext Advanced Print Publisher 9.1.440/W Unicode)
/Title (The role of high-dose myeloablative chemotherapy with haematopoietic stem cell transplantation \(HSCT\) in children with central nervous system \(CNS\) tumours: protocol for a systematic review and meta-analysis)
/CrossMarkDomains#5B2#5D (springerlink.com)
/doi (10.1186/s13643-015-0155-7)
/CrossmarkDomainExclusive (true)
/Author (Caroline Main)
/CreationDate (D:20151119020349+08'00')
>>
endobj
2 0 obj
<<
/Dests 10 0 R
>>
endobj
3 0 obj
<<
/Type /Outlines
/Count 29
/Last 11 0 R
/First 12 0 R
>>
endobj
4 0 obj
<<
/Fields []
/DR <<
/Encoding <<
/PDFDocEncoding 13 0 R
>>
/Font <<
/Helv 14 0 R
/ZaDb 15 0 R
>>
>>
/DA (/Helv 0 Tf 0 g )
>>
endobj
5 0 obj
<<
/Type /OutputIntent
/OutputCondition (sRGB)
/DestOutputProfile 16 0 R
/S /GTS_PDFA1
/OutputConditionIdentifier (Custom)
/RegistryName ()
/Info (sRGB IEC61966-2.1)
>>
endobj
6 0 obj
<<
/Type /OutputIntent
/OutputCondition (sRGB)
/DestOutputProfile 16 0 R
/S /ISO_PDFE1
/OutputConditionIdentifier (Custom)
/RegistryName ()
/Info (sRGB IEC61966-2.1)
>>
endobj
7 0 obj
<<
/Length 27180
/Type /Metadata
/Subtype /XML
>>
stream
10.1186/s13643-015-0155-7
2015-11-19
true
springer.com
springerlink.com
Children,Central nervous system tumours,High-dose chemotherapy,Haematopoietic stem cell transplantation,Systematic review
Acrobat Distiller 10.1.5 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version)
2015-11-19
true
10.1186/s13643-015-0155-7
springer.com
springerlink.com
http://dx.doi.org/10.1186/s13643-015-0155-7
10.1186/s13643-015-0155-7
2046-4053
journal
Systematic Reviews
Main et al.
application/pdf
10.1186/s13643-015-0155-7
Systematic Reviews
Systematic Reviews, 2015, doi:10.1186/s13643-015-0155-7
Children
Central nervous system tumours
High-dose chemotherapy
Haematopoietic stem cell transplantation
Systematic review
The role of high-dose myeloablative chemotherapy with haematopoietic stem cell transplantation (HSCT) in children with central nervous system (CNS) tumours: protocol for a systematic review and meta-analysis
Caroline Main
Jayne S. Wilson
Simon P. Stevens
Aimee E. Houlton
Martin English
Pamela R. Kearns
Bob Phillips
Barry Pizer
Sophie Wilne
Keith Wheatley
Arbortext Advanced Print Publisher 9.1.440/W Unicode
2015-11-20T13:45:22+01:00
2015-11-19T02:03:49+08:00
2015-11-20T13:45:22+01:00
uuid:454d4ae2-76c9-4af3-969c-01302f53b23b
uuid:087797f5-5998-4a5b-ad3f-6049eabbebdd
default
1
converted
uuid:6d1a53c2-eb79-4b4f-95db-15eaa49efa76
converted to PDF/A-2b
pdfToolbox
2015-11-19T02:08:30+08:00
2
B
http://ns.adobe.com/pdf/1.3/
pdf
Adobe PDF Schema
internal
A name object indicating whether the document has been modified to include trapping information
Trapped
Text
http://ns.adobe.com/xap/1.0/mm/
xmpMM
XMP Media Management Schema
internal
UUID based identifier for specific incarnation of a document
InstanceID
URI
internal
The common identifier for all versions and renditions of a document.
DocumentID
URI
internal
The common identifier for all versions and renditions of a document.
OriginalDocumentID
URI
http://www.aiim.org/pdfa/ns/id/
pdfaid
PDF/A ID Schema
internal
Part of PDF/A standard
part
Integer
internal
Amendment of PDF/A standard
amd
Text
internal
Conformance level of PDF/A standard
conformance
Text
Springer ORCiD Schema
http://springer.com/ns/xmpExtensions/1.0/
springer
authorInfo
AuthorInformation
external
Author information: contains the name of each author and his/her ORCiD (ORCiD: Open Researcher and Contributor ID). An ORCiD is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors.
AuthorInformation
http://springer.com/ns/xmpExtensions/1.0/authorinfo/
author
Specifies the types of author information: name and ORCID of an author.
name
Text
Gives the name of an author.
orcid
URI
Gives the ORCID of an author.
http://ns.adobe.com/pdfx/1.3/
pdfx
PDF/X ID Schema
internal
ID of PDF/X standard
GTS_PDFXVersion
Text
internal
Conformance level of PDF/X standard
GTS_PDFXConformance
Text
internal
Company creating the PDF
Company
Text
internal
Date when document was last modified
SourceModified
Text
external
Mirrors crossmark:CrosMarkDomains
CrossMarkDomains
Seq Text
external
Mirrors crossmark:CrossmarkDomainExclusive
CrossmarkDomainExclusive
Text
external
Mirrors crossmark:MajorVersionDate
CrossmarkMajorVersionDate
Text
internal
Mirrors crossmark:DOI
doi
Text
http://crossref.org/crossmark/1.0/
crossmark
crossmark
internal
CrossMarkDomains
CrossMarkDomains
Seq Text
internal
CrossmarkDomainExclusive
CrossmarkDomainExclusive
Text
internal
Usual same as prism:doi
DOI
Text
external
The date when a publication was published.
MajorVersionDate
Text
http://prismstandard.org/namespaces/basic/2.0/
prism
Prism
external
The aggregation type specifies the unit of aggregation for a content collection.
Comment
PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element.
Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary.
aggregationType
Text
external
Copyrigh
copyright
Text
external
The Digital Object Identifier for the article.
The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only.
If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL).
doi
Text
external
ISSN for an electronic version of the issue in which the resource occurs.
Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version. See prism:issn.
issn
Text
external
Title of the magazine, or other publication, in which a resource was/will be published.
Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date.
Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.”
publicationName
Text
external
This element provides the url for an article or unit of content.
The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element.
NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary.
url
Text
endstream
endobj
8 0 obj
<<
/Type /Pages
/Count 8
/Kids [17 0 R 18 0 R 19 0 R 20 0 R 21 0 R 22 0 R 23 0 R 24 0 R]
>>
endobj
10 0 obj
<<
/Kids [25 0 R 26 0 R]
>>
endobj
11 0 obj
<<
/C [0 0 0]
/Parent 3 0 R
/F 0
/Title
/Dest
/Prev 27 0 R
/Count 0
>>
endobj
12 0 obj
<<
/Next 28 0 R
/C [0 0 0]
/Parent 3 0 R
/F 0
/Title
/Dest
/Count 3
/Last 29 0 R
/First 30 0 R
>>
endobj
13 0 obj
<<
/Type /Encoding
/Differences [24 /breve /caron /circumflex /dotaccent /hungarumlaut /ogonek /ring /tilde 39
/quotesingle 96 /grave 128 /bullet /dagger /daggerdbl /ellipsis /emdash /endash
/florin /fraction /guilsinglleft /guilsinglright /minus /perthousand /quotedblbase /quotedblleft /quotedblright /quoteleft
/quoteright /quotesinglbase /trademark /fi /fl /Lslash /OE /Scaron /Ydieresis /Zcaron
/dotlessi /lslash /oe /scaron /zcaron 160 /Euro 164 /currency 166
/brokenbar 168 /dieresis /copyright /ordfeminine 172 /logicalnot /.notdef /registered /macron
/degree /plusminus /twosuperior /threesuperior /acute /mu 183 /periodcentered /cedilla /onesuperior
/ordmasculine 188 /onequarter /onehalf /threequarters 192 /Agrave /Aacute /Acircumflex /Atilde
/Adieresis /Aring /AE /Ccedilla /Egrave /Eacute /Ecircumflex /Edieresis /Igrave /Iacute
/Icircumflex /Idieresis /Eth /Ntilde /Ograve /Oacute /Ocircumflex /Otilde /Odieresis /multiply
/Oslash /Ugrave /Uacute /Ucircumflex /Udieresis /Yacute /Thorn /germandbls /agrave /aacute
/acircumflex /atilde /adieresis /aring /ae /ccedilla /egrave /eacute /ecircumflex /edieresis
/igrave /iacute /icircumflex /idieresis /eth /ntilde /ograve /oacute /ocircumflex /otilde
/odieresis /divide /oslash /ugrave /uacute /ucircumflex /udieresis /yacute /thorn /ydieresis]
>>
endobj
14 0 obj
<<
/BaseFont /Helvetica
/Type /Font
/Subtype /Type1
/Encoding 13 0 R
/Name /Helv
>>
endobj
15 0 obj
<<
/BaseFont /ZapfDingbats
/Type /Font
/Subtype /Type1
/Name /ZaDb
>>
endobj
16 0 obj
<<
/Length 2574
/N 3
/Filter /FlateDecode
/Range [0 1 0 1 0 1]
>>
stream
HyTSwoɞc
[5laQIBHADED2mtFOE.c}088GNg9w߽ '0 ֠Jb
2y.-;!KZ ^i"L0-
@8(r;q7Ly&Qq4j|9
V)gB0iW8#8wթ8_٥ʨQQj@&A)/g>'K t;\
ӥ$պFZUn(4T%)뫔0C&Zi8bxEB;Pӓ̹Aom?W=
x- [ 0}y)7ta>jT7@tܛ`q2ʀ&6ZLĄ?_yxg)˔zçLU*uSkSeO4?c. R
߁-25 S>ӣVd`rn~Y&+`;A4 A9 =-tl`;~p Gp| [`L`< "AYA+Cb(R, *T2B-
ꇆnQt}MA0alSx k&^>0|>_',G!"F$H:R!zFQd?r9\A&GrQhE]a4zBgE#H *B=0HIpp0MxJ$D1D, VĭKĻYdE"EI2EBGt4MzNr!YK ?%_(0J:EAiQ(()ӔWT6U@P+!~mDeԴ!hӦh/']B/ҏӿ?a0nhF!X8܌kc&5S6lIa2cKMA!E#ƒdV(kel
}}Cq9
N')].uJr
wG xR^[oƜchg`>b$*~ :Eb~,m,-ݖ,Y¬*6X[ݱF=3뭷Y~dó tizf6~`{v.Ng#{}}jc1X6fm;'_9 r:8q:˜O:ϸ8uJqnv=MmR 4
n3ܣkGݯz=[==<=GTB(/S,]6*-W:#7*e^YDY}UjAyT`#D="b{ų+ʯ:!kJ4Gmt}uC%K7YVfFY.=b?SƕƩȺy
چk5%4m7lqlioZlG+Zzmzy]?uuw|"űNwW&e֥ﺱ*|j5kyݭǯg^ykEklD_p߶7Dmo꿻1ml{Mś
nLl<9O [$h՛BdҞ@iءG&vVǥ8nRĩ7u\ЭD- u`ֲK³8%yhYѹJº;.!
zpg_XQKFAǿ=ȼ:ɹ8ʷ6˶5̵5͵6ζ7ϸ9к<Ѿ?DINU\dlvۀ܊ݖޢ)߯6DScs
2F[p(@Xr4Pm8Ww)Km
endstream
endobj
17 0 obj
<<
/Contents 31 0 R
/Type /Page
/Resources <<
/Font <<
/F1 32 0 R
/F2 33 0 R
/F3 34 0 R
/F4 35 0 R
>>
/XObject <<
/Xf1 36 0 R
>>
>>
/Annots [37 0 R 38 0 R 39 0 R]
/Parent 8 0 R
/MediaBox [0 0 595 842]
>>
endobj
18 0 obj
<<
/CropBox [0 0 595.276 793.701]
/Parent 8 0 R
/Type /Page
/Contents [40 0 R 41 0 R 42 0 R 43 0 R 44 0 R 45 0 R 46 0 R 47 0 R]
/Resources <<
/ExtGState <<
/GS17 48 0 R
/GS19 49 0 R
/GS15 50 0 R
/GS7 51 0 R
/GS13 52 0 R
/GS9 53 0 R
/GS11 54 0 R
>>
/XObject <<
/Im1 55 0 R
>>
/ProcSet [/PDF /Text /ImageC /ImageB /ImageI]
/ColorSpace <<
/DefaultCMYK [/ICCBased 56 0 R]
>>
/Font <<
/F1 57 0 R
/F2 58 0 R
/F3 59 0 R
/F4 60 0 R
/F5 61 0 R
/F7 62 0 R
>>
/Properties <<
/MC1 63 0 R
/MC2 64 0 R
/MC3 65 0 R
/MC4 66 0 R
/MC6 67 0 R
/MC5 68 0 R
/MC7 69 0 R
>>
>>
/Thumb 70 0 R
/MediaBox [0 0 595.276 793.701]
/Annots [71 0 R 72 0 R 73 0 R 74 0 R 75 0 R]
/Rotate 0
>>
endobj
19 0 obj
<<
/CropBox [0 0 595.276 793.701]
/Parent 8 0 R
/Type /Page
/Contents 76 0 R
/Resources <<
/ExtGState <<
/GS4 77 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
/ColorSpace <<
/DefaultCMYK [/ICCBased 56 0 R]
>>
/Font <<
/F1 57 0 R
/F2 58 0 R
/F4 60 0 R
/F5 61 0 R
/F9 62 0 R
/F8 78 0 R
/F7 79 0 R
>>
>>
/Thumb 80 0 R
/MediaBox [0 0 595.276 793.701]
/Annots [81 0 R 82 0 R 83 0 R 84 0 R 85 0 R 86 0 R 87 0 R 88 0 R 89 0 R 90 0 R
91 0 R 92 0 R 93 0 R 94 0 R 95 0 R 96 0 R 97 0 R]
/Rotate 0
>>
endobj
20 0 obj
<<
/CropBox [0 0 595.276 793.701]
/Parent 8 0 R
/Type /Page
/Contents 98 0 R
/Resources <<
/ExtGState <<
/GS4 77 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
/ColorSpace <<
/DefaultCMYK [/ICCBased 56 0 R]
>>
/Font <<
/F1 62 0 R
/F2 58 0 R
/F4 60 0 R
/F5 61 0 R
/F9 99 0 R
/F8 78 0 R
/F7 79 0 R
>>
>>
/Thumb 100 0 R
/MediaBox [0 0 595.276 793.701]
/Annots [101 0 R 102 0 R 103 0 R 104 0 R 105 0 R]
/Rotate 0
>>
endobj
21 0 obj
<<
/CropBox [0 0 595.276 793.701]
/Parent 8 0 R
/Type /Page
/Contents 106 0 R
/Resources <<
/ExtGState <<
/GS4 77 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
/ColorSpace <<
/DefaultCMYK [/ICCBased 56 0 R]
>>
/Font <<
/F1 57 0 R
/F2 58 0 R
/F10 107 0 R
/F4 60 0 R
/F11 108 0 R
/F5 61 0 R
/F9 99 0 R
/F8 78 0 R
/F12 62 0 R
/F7 79 0 R
>>
>>
/Thumb 109 0 R
/MediaBox [0 0 595.276 793.701]
/Annots [110 0 R 111 0 R 112 0 R]
/Rotate 0
>>
endobj
22 0 obj
<<
/CropBox [0 0 595.276 793.701]
/Parent 8 0 R
/Type /Page
/Contents 113 0 R
/Resources <<
/ExtGState <<
/GS4 77 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
/ColorSpace <<
/DefaultCMYK [/ICCBased 56 0 R]
>>
/Font <<
/F1 57 0 R
/F2 58 0 R
/F3 62 0 R
/F5 61 0 R
/F8 78 0 R
/F7 79 0 R
>>
>>
/Thumb 114 0 R
/MediaBox [0 0 595.276 793.701]
/Annots [115 0 R]
/Rotate 0
>>
endobj
23 0 obj
<<
/CropBox [0 0 595.276 793.701]
/Parent 8 0 R
/Type /Page
/Contents 116 0 R
/Resources <<
/ExtGState <<
/GS8 53 0 R
/GS4 77 0 R
/GS6 54 0 R
>>
/XObject <<
/Im2 117 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
/ColorSpace <<
/DefaultCMYK [/ICCBased 56 0 R]
>>
/Font <<
/F1 57 0 R
/F2 58 0 R
/F3 59 0 R
/F4 60 0 R
/F5 61 0 R
/F9 62 0 R
/F12 118 0 R
/F13 119 0 R
>>
/Properties <<
/MC8 120 0 R
>>
>>
/Thumb 121 0 R
/MediaBox [0 0 595.276 793.701]
/Rotate 0
>>
endobj
24 0 obj
<<
/CropBox [0 0 595.276 793.701]
/Parent 8 0 R
/Type /Page
/Contents 122 0 R
/Resources <<
/ExtGState <<
/GS15 123 0 R
/GS7 77 0 R
/GS13 48 0 R
/GS9 124 0 R
/GS11 125 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
/ColorSpace <<
/Cs10 [/DeviceN [/Cyan /Yellow /Black]
[/ICCBased 56 0 R]
126 0 R]
/Cs8 [/Separation /Black [/ICCBased 56 0 R]
127 0 R]
/Cs9 [/DeviceN [/Cyan /Magenta]
[/ICCBased 56 0 R]
128 0 R]
/DefaultCMYK [/ICCBased 56 0 R]
>>
/Font <<
/F1 62 0 R
/F2 58 0 R
/F3 59 0 R
/F4 60 0 R
/F5 61 0 R
/F14 129 0 R
/F15 130 0 R
/F12 118 0 R
>>
/Properties <<
/MC9 131 0 R
/MC10 132 0 R
>>
>>
/Thumb 133 0 R
/MediaBox [0 0 595.276 793.701]
/Annots [134 0 R 135 0 R]
/Rotate 0
>>
endobj
25 0 obj
<<
/Names [ 136 0 R 137 0 R 138 0 R 139 0 R 140 0 R
141 0 R 142 0 R 143 0 R 144 0 R 145 0 R
146 0 R 147 0 R 148 0 R 149 0 R 150 0 R
151 0 R 152 0 R 153 0 R 154 0 R 155 0 R
156 0 R 157 0 R 158 0 R 159 0 R 160 0 R
161 0 R 162 0 R 163 0 R 164 0 R 165 0 R
166 0 R 167 0 R 168 0 R 169 0 R 170 0 R
171 0 R 172 0 R 173 0 R 174 0 R 175 0 R
176 0 R 177 0 R 178 0 R 179 0 R 180 0 R
181 0 R 182 0 R 183 0 R 184 0 R 185 0 R
186 0 R 187 0 R 188 0 R 189 0 R 190 0 R
191 0 R 192 0 R 193 0 R 194 0 R 195 0 R
196 0 R 197 0 R 198 0 R 199 0 R]
/Limits [ ]
>>
endobj
26 0 obj
<<
/Names [ 200 0 R 201 0 R 202 0 R 203 0 R 204 0 R
205 0 R 206 0 R 207 0 R 208 0 R 209 0 R
210 0 R]
/Limits [ ]
>>
endobj
27 0 obj
<<
/Next 11 0 R
/C [0 0 0]
/Parent 3 0 R
/F 0
/Title
/Dest
/Prev 211 0 R
/Count 0
>>
endobj
28 0 obj
<<
/Next 212 0 R
/C [0 0 0]
/Parent 3 0 R
/F 0
/Title
/Dest
/Prev 12 0 R
/Count 0
>>
endobj
29 0 obj
<<
/C [0 0 0]
/Parent 12 0 R
/F 0
/Title
/Dest
/Prev 213 0 R
/Count 0
>>
endobj
30 0 obj
<<
/Next 213 0 R
/C [0 0 0]
/Parent 12 0 R
/F 0
/Title
/Dest
/Count 0
>>
endobj
31 0 obj
<<
/Length 1967
/Filter /FlateDecode
>>
stream
xXrFER3Ne,nL⸊" )i/ɌI"))@dKh 3ܾxhHqф t}s/G_@~Zuj5V[^?<2}:Aao]׀K=N66jp=uwGJ nGzn4k'֯6|a~vϺw}jö^aG^%/_pmy6!9;rC*.~ίރbw\g)`]+4OO3t>m'?(A=0@74Mnn-3XNKk2,d
03zONfoG6eC=Se2(Gf2ǂLNw{|||OqvaV}>2jq捖ȼz0x]W,^:VNV~\ӛܽ/4VO[*,8mÛ