%PDF-1.7
%
1 0 obj
<<
/PageMode /UseThumbs
/Metadata 2 0 R
/Pages 3 0 R
/PageLayout /SinglePage
/OpenAction 4 0 R
/Type /Catalog
>>
endobj
5 0 obj
<<
/CreationDate (D:20141205034750-08'00')
/Subject (International Journal of Cardiology, Accepted manuscript. doi:10.1016/j.ijcard.2014.11.196)
/Author (Keitaro Senoo)
/Creator (Elsevier)
/Producer (Acrobat Distiller 4.05 for Windows)
/ElsevierWebPDFSpecifications (6.4)
/ModDate (D:20141205194803+08'00')
/doi (10.1016/j.ijcard.2014.11.196)
/Title (Stroke risk reduction with oral anticoagulation using CHA2DS2-VASc in a Japanese AF population: a modeling analysis)
>>
endobj
2 0 obj
<<
/Length 5627
/Subtype /XML
/Type /Metadata
>>
stream
application/pdf
doi:10.1016/j.ijcard.2014.11.196
Stroke risk reduction with oral anticoagulation using CHA2DS2-VASc in a Japanese AF population: a modeling analysis
Keitaro Senoo
Deirdre A. Lane
Gregory Y.H. Lip
Dabigatran
rivaroxaban
apixaban
edoxaban
atrial fibrillation
stroke prevention
International Journal of Cardiology, Accepted manuscript. doi:10.1016/j.ijcard.2014.11.196
Elsevier Ireland Ltd
journal
International Journal of Cardiology
Copyright (c) 2014 Elsevier Ireland Ltd All rights reserved
0167-5273
10.1016/j.ijcard.2014.11.196
http://dx.doi.org/10.1016/j.ijcard.2014.11.196
6.4
10.1016/j.ijcard.2014.11.196
Elsevier
2014-12-05T03:47:50-08:00
2014-12-05T19:48:03+08:00
2014-12-05T19:48:03+08:00
True
Acrobat Distiller 4.05 for Windows
uuid:a4454289-42cb-4760-af89-929987742a76
uuid:0d6300d4-6cc2-4f9b-8bbd-a5db1c98dd1e
endstream
endobj
3 0 obj
<<
/Count 31
/Type /Pages
/Kids [6 0 R 7 0 R 8 0 R 9 0 R 10 0 R 11 0 R 12 0 R 13 0 R 14 0 R 15 0 R
16 0 R 17 0 R 18 0 R 19 0 R 20 0 R 21 0 R 22 0 R 23 0 R 24 0 R 25 0 R
26 0 R 27 0 R 28 0 R 29 0 R 30 0 R 31 0 R 32 0 R 33 0 R 34 0 R 35 0 R
36 0 R]
>>
endobj
4 0 obj
<<
/D [7 0 R /FitH -32768]
/S /GoTo
>>
endobj
6 0 obj
<<
/Contents 37 0 R
/Type /Page
/Resources <<
/Font <<
/F1 38 0 R
/F2 39 0 R
/F3 40 0 R
/F4 41 0 R
>>
/XObject <<
/Xf1 42 0 R
>>
>>
/Annots [43 0 R 44 0 R 45 0 R]
/Parent 3 0 R
/MediaBox [0 0 595 842]
>>
endobj
7 0 obj
<<
/CropBox [0 0 612 792]
/Annots [46 0 R 47 0 R]
/Parent 3 0 R
/Contents 48 0 R
/Rotate 0
/MediaBox [0 0 612 792]
/Thumb 49 0 R
/Resources 50 0 R
/Type /Page
>>
endobj
8 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [51 0 R 52 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi0 53 0 R
>>
/Font <<
/F1 54 0 R
/F2 55 0 R
/F3 56 0 R
/F4 57 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
9 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [58 0 R 59 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi1 53 0 R
>>
/Font <<
/F1 54 0 R
/F2 55 0 R
/F3 56 0 R
/F5 60 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
10 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [61 0 R 62 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi2 53 0 R
>>
/Font <<
/F1 54 0 R
/F2 55 0 R
/F3 56 0 R
/F4 57 0 R
/F5 60 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
11 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [63 0 R 64 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi3 53 0 R
>>
/Font <<
/F1 54 0 R
/F2 55 0 R
/F3 56 0 R
/F5 60 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
12 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [65 0 R 66 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi4 53 0 R
>>
/Font <<
/F1 54 0 R
/F2 55 0 R
/F3 56 0 R
/F5 60 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
13 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [67 0 R 68 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi5 53 0 R
>>
/Font <<
/F1 54 0 R
/F2 55 0 R
/F3 56 0 R
/F4 57 0 R
/F5 60 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
14 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [69 0 R 70 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi6 53 0 R
>>
/Font <<
/F1 54 0 R
/F2 55 0 R
/F3 56 0 R
/F5 60 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
15 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [71 0 R 72 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi7 53 0 R
>>
/Font <<
/F1 54 0 R
/F2 55 0 R
/F3 56 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
16 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [73 0 R 74 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi8 53 0 R
>>
/Font <<
/F1 54 0 R
/F2 55 0 R
/F3 56 0 R
/F5 60 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
17 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [75 0 R 76 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi9 53 0 R
>>
/Font <<
/F1 54 0 R
/F3 56 0 R
/F5 60 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
18 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [77 0 R 78 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi10 53 0 R
>>
/Font <<
/F1 54 0 R
/F3 56 0 R
/F5 60 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
19 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [79 0 R 80 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi11 53 0 R
>>
/Font <<
/F1 54 0 R
/F3 56 0 R
/F5 60 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
20 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [81 0 R 82 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi12 53 0 R
>>
/Font <<
/F1 54 0 R
/F3 56 0 R
/F5 60 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
21 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [83 0 R 84 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi13 53 0 R
>>
/Font <<
/F1 54 0 R
/F3 56 0 R
/F4 57 0 R
/F5 60 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
22 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [85 0 R 86 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi14 53 0 R
>>
/Font <<
/F1 54 0 R
/F3 56 0 R
/F5 60 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
23 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [87 0 R 88 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi15 53 0 R
>>
/Font <<
/F1 54 0 R
/F2 55 0 R
/F3 56 0 R
/F5 60 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
24 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [89 0 R 90 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi16 53 0 R
>>
/Font <<
/F1 54 0 R
/F2 55 0 R
/F3 56 0 R
/F5 60 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
25 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [91 0 R 92 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi17 53 0 R
>>
/Font <<
/F1 54 0 R
/F2 55 0 R
/F3 56 0 R
/F4 57 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
26 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [93 0 R 94 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi18 53 0 R
>>
/Font <<
/F1 54 0 R
/F3 56 0 R
/F4 57 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
27 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [95 0 R 96 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi19 53 0 R
>>
/Font <<
/F1 54 0 R
/F3 56 0 R
/F4 57 0 R
/F5 60 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
28 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [97 0 R 98 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi20 53 0 R
>>
/Font <<
/F1 54 0 R
/F3 56 0 R
/F4 57 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
29 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [99 0 R 100 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi21 53 0 R
>>
/Font <<
/F1 54 0 R
/F3 56 0 R
/F4 57 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
30 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [101 0 R 102 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Image62 103 0 R
/Xi22 53 0 R
>>
/Font <<
/F1 54 0 R
/F3 56 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
31 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [104 0 R 105 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Image65 106 0 R
/Xi23 53 0 R
>>
/Font <<
/F1 54 0 R
/F3 56 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
32 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [107 0 R 108 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi24 53 0 R
>>
/Font <<
/F1 54 0 R
/F5 60 0 R
/F6 109 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
33 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [110 0 R 111 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi25 53 0 R
>>
/Font <<
/F1 54 0 R
/F6 109 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
34 0 obj
<<
/CropBox [0 0 841.92 595.32]
/Parent 3 0 R
/Tabs /S
/Contents [112 0 R 113 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 841.92 595.32]
/Resources <<
/XObject <<
/Xi26 53 0 R
>>
/Font <<
/F1 54 0 R
/F6 109 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
35 0 obj
<<
/CropBox [0 0 841.92 595.32]
/Parent 3 0 R
/Tabs /S
/Contents [114 0 R 115 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 841.92 595.32]
/Resources <<
/XObject <<
/Xi27 53 0 R
>>
/Font <<
/F1 54 0 R
/F6 109 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
36 0 obj
<<
/CropBox [0 0 595.32 841.92]
/Parent 3 0 R
/Tabs /S
/Contents [116 0 R 117 0 R]
/Rotate 0
/Group <<
/CS /DeviceRGB
/S /Transparency
/Type /Group
>>
/MediaBox [0 0 595.32 841.92]
/Resources <<
/XObject <<
/Xi28 53 0 R
>>
/Font <<
/F1 54 0 R
/F3 56 0 R
/F6 109 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
>>
/Type /Page
>>
endobj
37 0 obj
<<
/Length 2199
/Filter /FlateDecode
>>
stream
xX[s>xFyp4I]n( R" RIU/ I)!y=HIG6 .Ξw./{_JWk44Gk!u/{?_5hы%<|kt /xRɰݥ]A/*eO{
P;4nNm 7ݻOikq8>gEk5oiy+`z7+B()![P~0kX;tߏ4XS>}ߧpQ4Lmq4jhC3uG?(o~-#`JS#oΕ[RLbTm}N^O}jCQj|ZxRjKQU\ͯVaХu{֏ۍyGm؋;_Uj{OVj9A><èu\@b:UM9L/z\fWܛK/s%]oo~gҊ+IV-LE $]WV`[MŲc?Z#CPzG!Wc:}W
U{jn6
ZCR̺hJ_<.*s!ڂG^^(VrDzr!p2ͦкFT.rȔ|$q_o:L^a}O9{DΐF.9u5w&êIX9C)_p 8d ; g@˨:2aF㔟6q1K^
[E0vx`,Jct&)w
3\JoY>~c/`NՕ 2Xh3BOw\