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/Author (Alan M. Jones)
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/Keywords (macrocyclic ether; Mitsunobu; macrocyclisation)
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/Subject (Re-investigation of the 1H-NMR spectrum reported for 15-bromo-4-oxa-2,9-diaza-1\(2,4\)-pyrimidine-3\(1,3\)-benzenacyclononaphane \(2\) prepared via a Mitsunobu- mediated macroether cyclisation led to a proposed structural isomer \(3\). The title compound \(3\) was prepared via a two-step protocol and assigned using 1H, 13C-NMR and LC-MS.)
/Title (3-\({5-Bromo-4-[pyrrolidin-1-yl]pyrimidin-2-yl}amino\)phenol)
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2015-05-21T18:18:50+08:00
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macrocyclic ether; Mitsunobu; macrocyclisation
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3-({5-Bromo-4-[pyrrolidin-1-yl]pyrimidin-2-yl}amino)phenol
Alan M. Jones
Re-investigation of the 1H-NMR spectrum reported for 15-bromo-4-oxa-2,9-diaza-1(2,4)-pyrimidine-3(1,3)-benzenacyclononaphane (2) prepared via a Mitsunobu- mediated macroether cyclisation led to a proposed structural isomer (3). The title compound (3) was prepared via a two-step protocol and assigned using 1H, 13C-NMR and LC-MS.
macrocyclic ether
Mitsunobu
macrocyclisation
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