Wnt signalling in lung development and diseases

Research output: Contribution to journalEditorial


  • JE Pongracz
  • Robert Stockley

Colleges, School and Institutes


There are several signalling pathways involved in lung organogenesis including Notch, TGFbeta/BMP, Sonic hedgehog (Shh), FGF, EGF, and Wnt. Despite the widely acknowledged significance of Wnt signalling in embryonic lung development, the role of different Wnt pathways in lung pathologies has been slow to emerge. In this review, we will present a synopsis of current Wnt research with particular attention paid to the role of Wnt signals in lung development and in pulmonary diseases.


Original languageEnglish
Pages (from-to)15
Number of pages1
JournalRespiratory research
Publication statusPublished - 1 Jan 2006