Why do pregnant women participate in research? A patient participation investigation using Q-Methodology

Research output: Contribution to journalArticle

Authors

Colleges, School and Institutes

External organisations

  • Warwick Medical School, University of Warwick, Coventry, United Kingdom
  • Endocrinology & Metabolism; Warwick Medical School; University of Warwick & George Eliot Hospital; Coventry UK

Abstract

Background:
Patient participation in study design is paramount to design studies that are acceptable to patients. Despite an increase in research involving pregnant women, relatively little is known about the motivational factors that govern their decision to be involved in a clinical trial, compared to other patient groups.

Objective:
To better understand the viewpoints of pregnant women who take part in clinical trials.

Method:
We chose to use Q-Methodology, a method of exploring the structure of opinions surrounding a topic. We developed a set of 40 statements that encompassed the reasons why pregnant women might want to take part in research and 30 research participants from the PRiDE study (an observational trial investigating the role of micronutrients in gestational diabetes) were asked to rank them in order of agreement. The finished matrices from each participant were compared and analysed to produce capturing viewpoints.

Results:
About 30 women aged 19–40 involved in the PRiDE study completed the questionnaire. There were two overarching motivators that emerged: a willingness to help medical research and improve our knowledge of medical science, and having a personal connection to the disease, therefore a potential fear of being affected by it. A third, less significant viewpoint, was that of a lack of inconvenience being a motivating factor.

Conclusion and discussion:
Understanding what motivates pregnant women to decide to take part in a research study is valuable and helps researchers maximize their uptake and retention rates when designing a trial involving pregnant women.

Details

Original languageEnglish
JournalHealth Expectations
Early online date26 Feb 2016
Publication statusE-pub ahead of print - 26 Feb 2016

Keywords

  • consent, participation, patient choice, pregnancy research, Q-Methodology