What makes Cryptococcus gattii a pathogen?

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Colleges, School and Institutes

Abstract

Cryptococcosis is an invasive fungal infection of humans and other animals, typically caused by the species Cryptococcus neoformans in patients with impaired immunity. However, there is growing recognition of the importance of the related species C. gattii in causing infections in apparently immunocompetent individuals. In particular, an ongoing outbreak of cryptococcal disease in the Pacific Northwest region, which started in 1999, has driven an intense research effort into this previously neglected pathogen. Here, we discuss some of the recent discoveries in this organism from the Pacific Northwest region and highlight areas for future investigation.

Details

Original languageEnglish
JournalFEMS yeast research
Volume16
Issue number1
Early online date26 Nov 2015
Publication statusPublished - Feb 2016