Visuomotor adaptation during inactivation of the dentate nucleus

Research output: Contribution to journalArticlepeer-review

Authors

Colleges, School and Institutes

External organisations

  • University of Oxford

Abstract

RECENT experiments have suggested that the process of visuomotor adaptation depends on how a visual distortion is introduced. The cerebellum is thought to be involved in adapting to rapidly introduced visual distortions; however its role in adapting to a gradually introduced distortion is unknown. We tested adaptation to a sudden or a gradual introduction of a visual distortion, during reversible inactivation of a monkey's dentate nucleus. There was significant adaptation in both of these tasks without any lignocaine infusion and during saline infusions. However after inactivation the ability to adapt to either visual distortion was slightly impaired. This dysfunction was significant when the visuomotor distortion was introduced over several trials, suggesting that the cerebellum has a differential contribution to visual adaptation depending on the type of visuo-motor disturbance encountered.

Details

Original languageEnglish
Pages (from-to)1029-1034
Number of pages6
JournalNeuroReport
Volume10
Issue number5
Publication statusPublished - 6 Apr 1999

Keywords

  • Arm movements, Cerebellum, Monkey, Visuo-motor adaptation

ASJC Scopus subject areas