TY - JOUR
T1 - Vesicles in Nature and the Laboratory
T2 - Elucidation of Their Biological Properties and Synthesis of Increasingly Complex Synthetic Vesicles
AU - Fernandez-Trillo, Francisco
AU - Grover, Liam M.
AU - Stephenson-Brown, Alex
AU - Harrison, Paul
AU - Mendes, Paula M.
N1 - © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
PY - 2017/3/13
Y1 - 2017/3/13
N2 - The important role of vesicles in many aspects of cell function is well-recognized, but only recently have sophisticated imaging techniques begun to reveal their ubiquity in nature. While we further our understanding of the biological properties of vesicles and their physiological functions, increasingly elegant artificial vesicles are being developed for a wide range of technological applications and basic research. Herein, we examine the state of the art of biological and synthetic vesicles and place their biological features in the context of recent synthetic developments, thus providing a unique overview of these complex and rapidly developing fields. The challenges and opportunities associated with future biological and synthetic studies of vesicles are also presented.
AB - The important role of vesicles in many aspects of cell function is well-recognized, but only recently have sophisticated imaging techniques begun to reveal their ubiquity in nature. While we further our understanding of the biological properties of vesicles and their physiological functions, increasingly elegant artificial vesicles are being developed for a wide range of technological applications and basic research. Herein, we examine the state of the art of biological and synthetic vesicles and place their biological features in the context of recent synthetic developments, thus providing a unique overview of these complex and rapidly developing fields. The challenges and opportunities associated with future biological and synthetic studies of vesicles are also presented.
KW - Biological vesicles
KW - Compartmentalization
KW - Polymersomes
KW - Synthetic cells
KW - Synthetic vesicles
UR - http://www.scopus.com/inward/record.url?scp=85013277449&partnerID=8YFLogxK
U2 - 10.1002/anie.201607825
DO - 10.1002/anie.201607825
M3 - Article
C2 - 27732763
SN - 1433-7851
VL - 56
SP - 203
EP - 229
JO - Angewandte Chemie (International Edition)
JF - Angewandte Chemie (International Edition)
IS - 12
ER -