Vascular adhesion protein 1 mediates binding of T cells to human hepatic endothelium
Research output: Contribution to journal › Article › peer-review
Colleges, School and Institutes
Molecules that regulate T-cell adhesion to hepatic endothelium and thereby recirculation of T cells to the liver are poorly understood. Because the adhesion molecule vascular adhesion protein-1 (VAP-1), which mediates lymphocyte binding to lymph node endothelium, is expressed on hepatic endothelium, it could play a role in regulating T-cell recruitment to the liver. The aim of this study was to investigate the distribution of VAP-1 expression in human liver and the ability of VAP-1 to support T-cell binding to hepatic endothelium in vitro.
|Number of pages||7|
|Publication status||Published - Feb 1996|
- Cell Adhesion, Endothelium, Endothelium, Vascular, Graft Rejection, Humans, Immunohistochemistry, Liver, Liver Cirrhosis, Biliary, Liver Transplantation, T-Lymphocytes, Vascular Cell Adhesion Molecule-1