Variation at the GABAA receptor gene, Rho1 (GABRR1) associated with susceptibility to bipolar schizoaffective disorder
Research output: Contribution to journal › Article
Authors
Colleges, School and Institutes
Abstract
We have previously reported evidence that variation at GABA(A) receptor genes is associated with susceptibility to bipolar disorder with schizophrenia-like psychotic features (Research Diagnostic Criteria (RDC) schizoaffective disorder, bipolar type) with gene-wide significance at GABRB1, GABRA4, GABRB3, GABRA5, and GABRR3. Here we provide suggestive evidence implicating a sixth member of the gene family, GABRR1 (gene-wide P = 0.0058; experiment-wide corrected significance P = 0.052).
Details
| Original language | English |
|---|---|
| Pages (from-to) | 1347-1349 |
| Number of pages | 3 |
| Journal | American Journal of Medical Genetics Part B: Neuropsychiatric Genetics |
| Volume | 153b |
| Issue number | 7 |
| Publication status | Published - 1 Jan 2010 |