Use cases, best practice and reporting standards for metabolomics in regulatory toxicology

Research output: Contribution to journalArticlepeer-review


  • Timothy M.D. Ebbels
  • Richard D. Beger
  • Drew R. Ekman
  • David J.T. Epps
  • Hennicke Kamp
  • Pim E.G. Leonards
  • George D. Loizou
  • James I. MacRae
  • Bennard van Ravenzwaay
  • Philippe Rocca-Serra
  • Reza M. Salek
  • Tilmann Walk
  • Ralf J.M. Weber

Colleges, School and Institutes

External organisations

  • Phenome Centre Birmingham
  • Imperial College London
  • NCTR
  • U.S. Environmental Protection Agency
  • Vrije Universiteit Amsterdam
  • Health and Safety Executive
  • The Francis Crick Institute
  • University of Oxford
  • International Agency for Research on Cancer
  • BASF Metabolome Solutions GmbH


Lack of best practice guidelines currently limits the application of metabolomics in the regulatory sciences. Here, the MEtabolomics standaRds Initiative in Toxicology (MERIT) proposes methods and reporting standards for several important applications of metabolomics in regulatory toxicology.


Original languageEnglish
Article number3041
JournalNature Communications
Issue number1
Publication statusPublished - 1 Dec 2019