Unravelling how glucocorticoids work in rheumatoid arthritis

Research output: Contribution to journalArticle

Authors

Colleges, School and Institutes

External organisations

  • University of Sydney

Abstract

Using mice with targeted deletion of the glucocorticoid receptor, a new study has examined the cell types that mediate the anti-arthritic effects of therapeutic glucocorticoids. Surprisingly, in the serum transfer-induced arthritis model, glucocorticoids target stromal cells rather than immune cells.

Details

Original languageEnglish
Pages (from-to)1759-4804
Number of pages2
JournalNature Reviews Rheumatology
Publication statusPublished - 4 Sep 2018