TY - JOUR
T1 - Ultrasound capsule endoscopy
T2 - sounding out the future
AU - Cox, Benjamin F.
AU - Stewart, Fraser
AU - Lay, Holly
AU - Cummins, Gerard
AU - Newton, Ian P.
AU - Desmulliez, Marc P. Y.
AU - Steele, Robert J. C.
AU - Nathke, Inke
AU - Cochran, Sandy
PY - 2017/5/31
Y1 - 2017/5/31
N2 - Video capsule endoscopy (VCE) has been of immense benefit in the diagnosis and management of gastrointestinal (GI) disorders since its introduction in 2001. However, it suffers from a number of well recognized deficiencies. Amongst these is the limited capability of white light imaging, which is restricted to analysis of the mucosal surface. Current capsule endoscopes are dependent on visual manifestation of disease and limited in regards to transmural imaging and detection of deeper pathology. Ultrasound capsule endoscopy (USCE) has the potential to overcome surface only imaging and provide transmural scans of the GI tract. The integration of high frequency microultrasound (µUS) into capsule endoscopy would allow high resolution transmural images and provide a means of both qualitative and quantitative assessment of the bowel wall. Quantitative ultrasound (QUS) can provide data in an objective and measurable manner, potentially reducing lengthy interpretation times by incorporation into an automated diagnostic process. The research described here is focused on the development of USCE and other complementary diagnostic and therapeutic modalities. Presently investigations have entered a preclinical phase with laboratory investigations running concurrently.
AB - Video capsule endoscopy (VCE) has been of immense benefit in the diagnosis and management of gastrointestinal (GI) disorders since its introduction in 2001. However, it suffers from a number of well recognized deficiencies. Amongst these is the limited capability of white light imaging, which is restricted to analysis of the mucosal surface. Current capsule endoscopes are dependent on visual manifestation of disease and limited in regards to transmural imaging and detection of deeper pathology. Ultrasound capsule endoscopy (USCE) has the potential to overcome surface only imaging and provide transmural scans of the GI tract. The integration of high frequency microultrasound (µUS) into capsule endoscopy would allow high resolution transmural images and provide a means of both qualitative and quantitative assessment of the bowel wall. Quantitative ultrasound (QUS) can provide data in an objective and measurable manner, potentially reducing lengthy interpretation times by incorporation into an automated diagnostic process. The research described here is focused on the development of USCE and other complementary diagnostic and therapeutic modalities. Presently investigations have entered a preclinical phase with laboratory investigations running concurrently.
KW - capsule endoscopy
KW - diagnosis
KW - gastrointestinal (GI)
KW - ultrasound (US)
KW - ultrasound capsule endoscopy (USCE)
UR - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000408638700009&KeyUID=WOS:000408638700009
U2 - 10.21037/atm.2017.04.21
DO - 10.21037/atm.2017.04.21
M3 - Article
VL - 5
SP - 1
EP - 9
JO - Annals of Translational Medicine
JF - Annals of Translational Medicine
IS - 9
M1 - 201
ER -