Twenty years of bacterial genome sequencing

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Twenty years of bacterial genome sequencing. / Loman, Nicholas J; Pallen, Mark J.

In: Nature Reviews Microbiology, Vol. 13, No. 12, 12.2015, p. 787-94.

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Loman, Nicholas J ; Pallen, Mark J. / Twenty years of bacterial genome sequencing. In: Nature Reviews Microbiology. 2015 ; Vol. 13, No. 12. pp. 787-94.

Bibtex

@article{037da5fe27874551a4d493a729d1978f,
title = "Twenty years of bacterial genome sequencing",
abstract = "Twenty years ago, the publication of the first bacterial genome sequence, from Haemophilus influenzae, shook the world of bacteriology. In this Timeline, we review the first two decades of bacterial genome sequencing, which have been marked by three revolutions: whole-genome shotgun sequencing, high-throughput sequencing and single-molecule long-read sequencing. We summarize the social history of sequencing and its impact on our understanding of the biology, diversity and evolution of bacteria, while also highlighting spin-offs and translational impact in the clinic. We look forward to a 'sequencing singularity', where sequencing becomes the method of choice for as-yet unthinkable applications in bacteriology and beyond.",
keywords = "DNA, Bacterial, Genome, Bacterial, History, 20th Century, History, 21st Century, Humans, Molecular Epidemiology, Molecular Typing, Sequence Analysis, DNA, Historical Article, Journal Article, Research Support, Non-U.S. Gov't",
author = "Loman, {Nicholas J} and Pallen, {Mark J}",
year = "2015",
month = dec,
doi = "10.1038/nrmicro3565",
language = "English",
volume = "13",
pages = "787--94",
journal = "Nature Reviews Microbiology",
issn = "1740-1526",
publisher = "Nature Publishing Group",
number = "12",

}

RIS

TY - JOUR

T1 - Twenty years of bacterial genome sequencing

AU - Loman, Nicholas J

AU - Pallen, Mark J

PY - 2015/12

Y1 - 2015/12

N2 - Twenty years ago, the publication of the first bacterial genome sequence, from Haemophilus influenzae, shook the world of bacteriology. In this Timeline, we review the first two decades of bacterial genome sequencing, which have been marked by three revolutions: whole-genome shotgun sequencing, high-throughput sequencing and single-molecule long-read sequencing. We summarize the social history of sequencing and its impact on our understanding of the biology, diversity and evolution of bacteria, while also highlighting spin-offs and translational impact in the clinic. We look forward to a 'sequencing singularity', where sequencing becomes the method of choice for as-yet unthinkable applications in bacteriology and beyond.

AB - Twenty years ago, the publication of the first bacterial genome sequence, from Haemophilus influenzae, shook the world of bacteriology. In this Timeline, we review the first two decades of bacterial genome sequencing, which have been marked by three revolutions: whole-genome shotgun sequencing, high-throughput sequencing and single-molecule long-read sequencing. We summarize the social history of sequencing and its impact on our understanding of the biology, diversity and evolution of bacteria, while also highlighting spin-offs and translational impact in the clinic. We look forward to a 'sequencing singularity', where sequencing becomes the method of choice for as-yet unthinkable applications in bacteriology and beyond.

KW - DNA, Bacterial

KW - Genome, Bacterial

KW - History, 20th Century

KW - History, 21st Century

KW - Humans

KW - Molecular Epidemiology

KW - Molecular Typing

KW - Sequence Analysis, DNA

KW - Historical Article

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

U2 - 10.1038/nrmicro3565

DO - 10.1038/nrmicro3565

M3 - Article

C2 - 26548914

VL - 13

SP - 787

EP - 794

JO - Nature Reviews Microbiology

JF - Nature Reviews Microbiology

SN - 1740-1526

IS - 12

ER -