Tuning the aggregation behavior of pH-responsive micelles by copolymerization

Research output: Contribution to journalArticlepeer-review

Standard

Tuning the aggregation behavior of pH-responsive micelles by copolymerization. / Wright, Daniel B.; Patterson, Joseph P.; Pitto-Barry, Anais; Cotanda, Pepa; Chassenieux, Christophe; Colombani, Olivier; O'Reilly, Rachel K.

In: Polymer Chemistry, Vol. 6, No. 14, 14.04.2015, p. 2761-2768.

Research output: Contribution to journalArticlepeer-review

Harvard

Wright, DB, Patterson, JP, Pitto-Barry, A, Cotanda, P, Chassenieux, C, Colombani, O & O'Reilly, RK 2015, 'Tuning the aggregation behavior of pH-responsive micelles by copolymerization', Polymer Chemistry, vol. 6, no. 14, pp. 2761-2768. https://doi.org/10.1039/c4py01782j

APA

Wright, D. B., Patterson, J. P., Pitto-Barry, A., Cotanda, P., Chassenieux, C., Colombani, O., & O'Reilly, R. K. (2015). Tuning the aggregation behavior of pH-responsive micelles by copolymerization. Polymer Chemistry, 6(14), 2761-2768. https://doi.org/10.1039/c4py01782j

Vancouver

Wright DB, Patterson JP, Pitto-Barry A, Cotanda P, Chassenieux C, Colombani O et al. Tuning the aggregation behavior of pH-responsive micelles by copolymerization. Polymer Chemistry. 2015 Apr 14;6(14):2761-2768. https://doi.org/10.1039/c4py01782j

Author

Wright, Daniel B. ; Patterson, Joseph P. ; Pitto-Barry, Anais ; Cotanda, Pepa ; Chassenieux, Christophe ; Colombani, Olivier ; O'Reilly, Rachel K. / Tuning the aggregation behavior of pH-responsive micelles by copolymerization. In: Polymer Chemistry. 2015 ; Vol. 6, No. 14. pp. 2761-2768.

Bibtex

@article{664dabe898c84d4f86244efe3ad8dbb7,
title = "Tuning the aggregation behavior of pH-responsive micelles by copolymerization",
abstract = "Amphiphilic diblock copolymers, poly(2-(diethylamino)ethyl methacrylate-co-2-(dimethylamino)ethyl methacrylate)-b-poly(2-(dimethylamino)ethyl methacrylate), P(DEAEMA-co-DMAEMA)-b-PDMAEMA with various amounts of DEAEMA have been synthesized by RAFT polymerization. Their micellization in water has been investigated by scattering measurements over a wide pH range. It appeared that the polymers self-assembled into pH sensitive star like micelles. For a given composition, when the pH is varied the extent of aggregation can be tuned reversibly by orders of magnitude. By varying the copolymer composition in the hydrophobic block, the onset and extent of aggregation were shifted with respect to pH. This class of diblock copolymer offers the possibility to select the range of stimuli-responsiveness that is useful for a given application, which can rarely be achieved with conventional diblock copolymers consisting of homopolymeric blocks.",
author = "Wright, {Daniel B.} and Patterson, {Joseph P.} and Anais Pitto-Barry and Pepa Cotanda and Christophe Chassenieux and Olivier Colombani and O'Reilly, {Rachel K.}",
year = "2015",
month = apr,
day = "14",
doi = "10.1039/c4py01782j",
language = "English",
volume = "6",
pages = "2761--2768",
journal = "Polymer Chemistry",
issn = "1759-9954",
publisher = "Royal Society of Chemistry",
number = "14",

}

RIS

TY - JOUR

T1 - Tuning the aggregation behavior of pH-responsive micelles by copolymerization

AU - Wright, Daniel B.

AU - Patterson, Joseph P.

AU - Pitto-Barry, Anais

AU - Cotanda, Pepa

AU - Chassenieux, Christophe

AU - Colombani, Olivier

AU - O'Reilly, Rachel K.

PY - 2015/4/14

Y1 - 2015/4/14

N2 - Amphiphilic diblock copolymers, poly(2-(diethylamino)ethyl methacrylate-co-2-(dimethylamino)ethyl methacrylate)-b-poly(2-(dimethylamino)ethyl methacrylate), P(DEAEMA-co-DMAEMA)-b-PDMAEMA with various amounts of DEAEMA have been synthesized by RAFT polymerization. Their micellization in water has been investigated by scattering measurements over a wide pH range. It appeared that the polymers self-assembled into pH sensitive star like micelles. For a given composition, when the pH is varied the extent of aggregation can be tuned reversibly by orders of magnitude. By varying the copolymer composition in the hydrophobic block, the onset and extent of aggregation were shifted with respect to pH. This class of diblock copolymer offers the possibility to select the range of stimuli-responsiveness that is useful for a given application, which can rarely be achieved with conventional diblock copolymers consisting of homopolymeric blocks.

AB - Amphiphilic diblock copolymers, poly(2-(diethylamino)ethyl methacrylate-co-2-(dimethylamino)ethyl methacrylate)-b-poly(2-(dimethylamino)ethyl methacrylate), P(DEAEMA-co-DMAEMA)-b-PDMAEMA with various amounts of DEAEMA have been synthesized by RAFT polymerization. Their micellization in water has been investigated by scattering measurements over a wide pH range. It appeared that the polymers self-assembled into pH sensitive star like micelles. For a given composition, when the pH is varied the extent of aggregation can be tuned reversibly by orders of magnitude. By varying the copolymer composition in the hydrophobic block, the onset and extent of aggregation were shifted with respect to pH. This class of diblock copolymer offers the possibility to select the range of stimuli-responsiveness that is useful for a given application, which can rarely be achieved with conventional diblock copolymers consisting of homopolymeric blocks.

UR - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000351720100018&KeyUID=WOS:000351720100018

U2 - 10.1039/c4py01782j

DO - 10.1039/c4py01782j

M3 - Article

VL - 6

SP - 2761

EP - 2768

JO - Polymer Chemistry

JF - Polymer Chemistry

SN - 1759-9954

IS - 14

ER -