Tuning coordination chemistry through the second sphere in designed metallocoiled coils

Research output: Contribution to journalArticle

Authors

Colleges, School and Institutes

External organisations

  • University of Birmingham

Abstract

The metal hydration state within a designed coiled coil can be progressively tuned across the full integer range (3 → 0 aqua ligands), by careful choice of a second sphere terminal residue, including the lesser used Trp. Potential implications include a four-fold change in MRI relaxivity when applied to lanthanide coiled coils.

Details

Original languageEnglish
Pages (from-to)3729-3732
Number of pages4
JournalChemical communications (Cambridge, England)
Volume56
Issue number26
Early online date26 Feb 2020
Publication statusPublished - 4 Apr 2020