Transfusion transmitted hepatitis E in a 'non-endemic' country

Research output: Contribution to journalArticle

Authors

  • EH Boxall
  • A Herborn
  • G Kochetu
  • S Ijaz
  • G-C Tao

Abstract

Indigenous hepatitis E is increasingly recognized in developed countries, where it may be a zoonosis. We describe the first case of transfusion-transmitted hepatitis E in the UK from a blood donor who had no history of recent travel abroad. Follow-up of the donor and recipients of the blood products was carried out using serological and molecular techniques. Acute hepatitis E was transmitted to one of two recipients. The infected patient would have received a larger volume of the donor's plasma. HEV subgenomic sequences carried by the donor and recipient were identical. This is the first case of post-transfusion hepatitis E in the UK. Secondary transmission of hepatitis E indigenous to a nonhyperendemic country may occur by blood transfusion. It is important that blood donors inform the transfusion service of all post-donation illnesses so that appropriate interventions can take place.

Details

Original languageEnglish
Pages (from-to)79-83
Number of pages5
JournalTransfusion Medicine
Volume16
Publication statusPublished - 1 Apr 2006