Towards a genomics-informed, real-time, global pathogen surveillance system

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Towards a genomics-informed, real-time, global pathogen surveillance system. / Gardy, Jennifer L; Loman, Nicholas.

In: Nature Reviews Genetics, Vol. 19, No. 1, 01.01.2018, p. 9-20.

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@article{88eb3cb28adb4e758359372eac5024e9,
title = "Towards a genomics-informed, real-time, global pathogen surveillance system",
abstract = "The recent Ebola and Zika epidemics demonstrate the need for the continuous surveillance, rapid diagnosis and real-time tracking of emerging infectious diseases. Fast, affordable sequencing of pathogen genomes - now a staple of the public health microbiology laboratory in well-resourced settings - can affect each of these areas. Coupling genomic diagnostics and epidemiology to innovative digital disease detection platforms raises the possibility of an open, global, digital pathogen surveillance system. When informed by a One Health approach, in which human, animal and environmental health are considered together, such a genomics-based system has profound potential to improve public health in settings lacking robust laboratory capacity.",
keywords = "Animals, Communicable Diseases, Emerging/epidemiology, Computer Systems, Environmental Health, Epidemics, Genomics, Hemorrhagic Fever, Ebola/epidemiology, High-Throughput Nucleotide Sequencing, Humans, Metagenomics, Models, Biological, Molecular Epidemiology, Public Health, Public Health Surveillance/methods",
author = "Gardy, {Jennifer L} and Nicholas Loman",
year = "2018",
month = "1",
day = "1",
doi = "10.1038/nrg.2017.88",
language = "English",
volume = "19",
pages = "9--20",
journal = "Nature Reviews Genetics",
issn = "1471-0056",
publisher = "Nature Publishing Group",
number = "1",

}

RIS

TY - JOUR

T1 - Towards a genomics-informed, real-time, global pathogen surveillance system

AU - Gardy, Jennifer L

AU - Loman, Nicholas

PY - 2018/1/1

Y1 - 2018/1/1

N2 - The recent Ebola and Zika epidemics demonstrate the need for the continuous surveillance, rapid diagnosis and real-time tracking of emerging infectious diseases. Fast, affordable sequencing of pathogen genomes - now a staple of the public health microbiology laboratory in well-resourced settings - can affect each of these areas. Coupling genomic diagnostics and epidemiology to innovative digital disease detection platforms raises the possibility of an open, global, digital pathogen surveillance system. When informed by a One Health approach, in which human, animal and environmental health are considered together, such a genomics-based system has profound potential to improve public health in settings lacking robust laboratory capacity.

AB - The recent Ebola and Zika epidemics demonstrate the need for the continuous surveillance, rapid diagnosis and real-time tracking of emerging infectious diseases. Fast, affordable sequencing of pathogen genomes - now a staple of the public health microbiology laboratory in well-resourced settings - can affect each of these areas. Coupling genomic diagnostics and epidemiology to innovative digital disease detection platforms raises the possibility of an open, global, digital pathogen surveillance system. When informed by a One Health approach, in which human, animal and environmental health are considered together, such a genomics-based system has profound potential to improve public health in settings lacking robust laboratory capacity.

KW - Animals

KW - Communicable Diseases, Emerging/epidemiology

KW - Computer Systems

KW - Environmental Health

KW - Epidemics

KW - Genomics

KW - Hemorrhagic Fever, Ebola/epidemiology

KW - High-Throughput Nucleotide Sequencing

KW - Humans

KW - Metagenomics

KW - Models, Biological

KW - Molecular Epidemiology

KW - Public Health

KW - Public Health Surveillance/methods

U2 - 10.1038/nrg.2017.88

DO - 10.1038/nrg.2017.88

M3 - Review article

C2 - 29129921

VL - 19

SP - 9

EP - 20

JO - Nature Reviews Genetics

JF - Nature Reviews Genetics

SN - 1471-0056

IS - 1

ER -