Tomographic Task-Related Functional Near-Infrared Spectroscopy in Acute Sport-Related Concussion: An Observational Case Study

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Tomographic Task-Related Functional Near-Infrared Spectroscopy in Acute Sport-Related Concussion : An Observational Case Study. / Forcione, Mario; Chiarelli, Antonio Maria; Perpetuini, David; Davies, David James; O'Halloran, Patrick; Hacker, David; Merla, Arcangelo; Belli, Antonio.

In: International Journal of Molecular Sciences, Vol. 21, No. 17, 6273, 29.08.2020.

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@article{705c2a7dce784208b8e1f3e59be29143,
title = "Tomographic Task-Related Functional Near-Infrared Spectroscopy in Acute Sport-Related Concussion: An Observational Case Study",
abstract = "Making decisions regarding return-to-play after sport-related concussion (SRC) based on resolution of symptoms alone can expose contact-sport athletes to further injury before their recovery is complete. Task-related functional near-infrared spectroscopy (fNIRS) could be used to scan for abnormalities in the brain activation patterns of SRC athletes and help clinicians to manage their return-to-play. This study aims to show a proof of concept of mapping brain activation, using tomographic task-related fNIRS, as part of the clinical assessment of acute SRC patients. A high-density frequency-domain optical device was used to scan 2 SRC patients, within 72 h from injury, during the execution of 3 neurocognitive tests used in clinical practice. The optical data were resolved into a tomographic reconstruction of the brain functional activation pattern, using diffuse optical tomography. Moreover, brain activity was inferred using single-subject statistical analyses. The advantages and limitations of the introduction of this optical technique into the clinical assessment of acute SRC patients are discussed.",
keywords = "DOT, Digit Span, Silent Word Generation, Symbol Search, TBI, WAIS-IV, diffuse optical tomography, fNIRS, return-to-play, traumatic brain injury",
author = "Mario Forcione and Chiarelli, {Antonio Maria} and David Perpetuini and Davies, {David James} and Patrick O'Halloran and David Hacker and Arcangelo Merla and Antonio Belli",
year = "2020",
month = aug,
day = "29",
doi = "10.3390/ijms21176273",
language = "English",
volume = "21",
journal = "International Journal of Molecular Sciences",
issn = "1661-6596",
publisher = "MDPI",
number = "17",

}

RIS

TY - JOUR

T1 - Tomographic Task-Related Functional Near-Infrared Spectroscopy in Acute Sport-Related Concussion

T2 - An Observational Case Study

AU - Forcione, Mario

AU - Chiarelli, Antonio Maria

AU - Perpetuini, David

AU - Davies, David James

AU - O'Halloran, Patrick

AU - Hacker, David

AU - Merla, Arcangelo

AU - Belli, Antonio

PY - 2020/8/29

Y1 - 2020/8/29

N2 - Making decisions regarding return-to-play after sport-related concussion (SRC) based on resolution of symptoms alone can expose contact-sport athletes to further injury before their recovery is complete. Task-related functional near-infrared spectroscopy (fNIRS) could be used to scan for abnormalities in the brain activation patterns of SRC athletes and help clinicians to manage their return-to-play. This study aims to show a proof of concept of mapping brain activation, using tomographic task-related fNIRS, as part of the clinical assessment of acute SRC patients. A high-density frequency-domain optical device was used to scan 2 SRC patients, within 72 h from injury, during the execution of 3 neurocognitive tests used in clinical practice. The optical data were resolved into a tomographic reconstruction of the brain functional activation pattern, using diffuse optical tomography. Moreover, brain activity was inferred using single-subject statistical analyses. The advantages and limitations of the introduction of this optical technique into the clinical assessment of acute SRC patients are discussed.

AB - Making decisions regarding return-to-play after sport-related concussion (SRC) based on resolution of symptoms alone can expose contact-sport athletes to further injury before their recovery is complete. Task-related functional near-infrared spectroscopy (fNIRS) could be used to scan for abnormalities in the brain activation patterns of SRC athletes and help clinicians to manage their return-to-play. This study aims to show a proof of concept of mapping brain activation, using tomographic task-related fNIRS, as part of the clinical assessment of acute SRC patients. A high-density frequency-domain optical device was used to scan 2 SRC patients, within 72 h from injury, during the execution of 3 neurocognitive tests used in clinical practice. The optical data were resolved into a tomographic reconstruction of the brain functional activation pattern, using diffuse optical tomography. Moreover, brain activity was inferred using single-subject statistical analyses. The advantages and limitations of the introduction of this optical technique into the clinical assessment of acute SRC patients are discussed.

KW - DOT

KW - Digit Span

KW - Silent Word Generation

KW - Symbol Search

KW - TBI

KW - WAIS-IV

KW - diffuse optical tomography

KW - fNIRS

KW - return-to-play

KW - traumatic brain injury

UR - http://www.scopus.com/inward/record.url?scp=85090179674&partnerID=8YFLogxK

U2 - 10.3390/ijms21176273

DO - 10.3390/ijms21176273

M3 - Article

C2 - 32872557

VL - 21

JO - International Journal of Molecular Sciences

JF - International Journal of Molecular Sciences

SN - 1661-6596

IS - 17

M1 - 6273

ER -