Tomographic Task-Related Functional Near-Infrared Spectroscopy in Acute Sport-Related Concussion: An Observational Case Study
Research output: Contribution to journal › Article › peer-review
- National Institute for Health Research Surgical Reconstruction and Microbiology Research Centre (NIHR-SRMRC)
- Departments of Cardiology, Sandwell and West Birmingham Hospitals NHS Trust and University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
- Birmingham Women's and Children's NHS Foundation Trust, Mindelsohn Way, Birmingham
- G. d'Annunzio University of Chieti-Pescara, Chieti, Italy.
Making decisions regarding return-to-play after sport-related concussion (SRC) based on resolution of symptoms alone can expose contact-sport athletes to further injury before their recovery is complete. Task-related functional near-infrared spectroscopy (fNIRS) could be used to scan for abnormalities in the brain activation patterns of SRC athletes and help clinicians to manage their return-to-play. This study aims to show a proof of concept of mapping brain activation, using tomographic task-related fNIRS, as part of the clinical assessment of acute SRC patients. A high-density frequency-domain optical device was used to scan 2 SRC patients, within 72 h from injury, during the execution of 3 neurocognitive tests used in clinical practice. The optical data were resolved into a tomographic reconstruction of the brain functional activation pattern, using diffuse optical tomography. Moreover, brain activity was inferred using single-subject statistical analyses. The advantages and limitations of the introduction of this optical technique into the clinical assessment of acute SRC patients are discussed.
|Journal||International Journal of Molecular Sciences|
|Publication status||Published - 29 Aug 2020|
- DOT, Digit Span, Silent Word Generation, Symbol Search, TBI, WAIS-IV, diffuse optical tomography, fNIRS, return-to-play, traumatic brain injury