The weekend effect in status epilepticus: a national cohort study

Research output: Contribution to journalArticlepeer-review


  • R Goulden
  • T Whitehouse
  • N Murphy
  • T Hayton
  • Z Khan
  • M Shyamsundar
  • C Snelson

External organisations

  • McGill University
  • Department of Critical Care medicine, University Hospital of Birmingham NHS trust, Birmingham, UK.
  • College of Medicine and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK; University Hospital Birmingham Foundation Trust, Queen Elizabeth Hospital Mindelsohn Way, Edgbaston, Birmingham, B15 2GW, UK; Department of Neurology, Sandwell and West Birmingham Hospitals NHS Trust, City Hospital, Dudley Road, Birmingham, B18 7QH, UK.
  • Department of Critical Care medicine, Queen's University, Belfast, UK.
  • Chair of Microbial Infection and Immunity, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.


Higher mortality following admission to hospital at the weekend has been reported for several conditions. It is unclear whether this variation is due to differences in patients or their care. Status epilepticus mandates hospital admission and usually critical care: its study might provide new insights into the nature of any weekend effect. We studied 20,922 adults admitted to UK critical care with status epilepticus from 2010 to 2015. We used multiple logistic regression to evaluate the association between weekend admission and in-hospital mortality, comparing university hospitals with other hospitals. There were 2462 in-hospital deaths (12%). There was no difference in mortality after weekend admission to university hospitals, adjusted odds ratio (95%CI) 0.99 (0.84-1.16), p = 0.89. Mortality was less after weekend admission than after admissions Monday to Friday in hospitals not associated with a university, adjusted odds ratio (95%CI) 0.74 (0.64-0.87), p = 0.0001. There is no evidence that adults admitted to UK critical care at the weekend in status epilepticus are more likely to die than similar patients admitted during the week.

Bibliographic note

© 2019 Association of Anaesthetists.


Original languageEnglish
Pages (from-to)468-472
Number of pages5
Issue number4
Early online date3 Jan 2019
Publication statusPublished - Apr 2019


  • Adult, Aged, Cohort Studies, Female, Hospital Mortality, Humans, Male, Middle Aged, Patient Admission, Status Epilepticus/mortality, Time Factors