The validity of estimating quadriceps volume from single MRI cross-sections in young men

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The validity of estimating quadriceps volume from single MRI cross-sections in young men. / Morse, CI; Degens, H; Jones, David.

In: European Journal of Applied Physiology, Vol. 100, 01.01.2007, p. 267-274.

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@article{63cd3d953d10416c82b9e60e3b68a1fd,
title = "The validity of estimating quadriceps volume from single MRI cross-sections in young men",
abstract = "Muscle size is often reported as a single anatomical cross-sectional area (ACSA), rather than volume measured with contiguous MRI scans. However, a single ACSA may provide an inadequate estimate of muscle mass. Therefore, we investigated whether quadriceps muscle volume can be adequately estimated from a single ACSA. In 18 adult males we derived regression equations from which estimates of volume were made. These equations were based on the direct assessment of volume using 11 transverse-plane MRI scans along the entire length of the femur (the gold standard). We estimated volume based on single scans at 40, 50 and 60% of femur length (from the distal end). All estimates of quadriceps volumes were highly correlated to the measured volume and demonstrated a low level of error. R-2 = 0.84, 0.93, 0.90 (all P <0.01), standard error of estimate (SEE) = 26.8 +/- 5.2, 12.5 +/- 5.4 and 9.9 +/- 5.7%, for single scans taken at 40, 50 and 60% of femur length respectively. In comparison, when volume was estimated using multiple MRI scans corresponding to the maximum ACSA of each muscle the estimate was even better [R-2 = 0.95 (P <0.01) and SEE = 4.5 +/- 2.7%]. Substituting ACSA from a single MRI scan at 60% of femur length into a previously determined regression equation allows for an estimation of muscle volume with a 10% error of estimate.",
keywords = "muscle mass, quadriceps volume, anatomical cross-sectional area",
author = "CI Morse and H Degens and David Jones",
year = "2007",
month = jan,
day = "1",
doi = "10.1007/s00421-007-0429-4",
language = "English",
volume = "100",
pages = "267--274",
journal = "European Journal of Applied Physiology",
issn = "1439-6319",
publisher = "Springer Verlag",

}

RIS

TY - JOUR

T1 - The validity of estimating quadriceps volume from single MRI cross-sections in young men

AU - Morse, CI

AU - Degens, H

AU - Jones, David

PY - 2007/1/1

Y1 - 2007/1/1

N2 - Muscle size is often reported as a single anatomical cross-sectional area (ACSA), rather than volume measured with contiguous MRI scans. However, a single ACSA may provide an inadequate estimate of muscle mass. Therefore, we investigated whether quadriceps muscle volume can be adequately estimated from a single ACSA. In 18 adult males we derived regression equations from which estimates of volume were made. These equations were based on the direct assessment of volume using 11 transverse-plane MRI scans along the entire length of the femur (the gold standard). We estimated volume based on single scans at 40, 50 and 60% of femur length (from the distal end). All estimates of quadriceps volumes were highly correlated to the measured volume and demonstrated a low level of error. R-2 = 0.84, 0.93, 0.90 (all P <0.01), standard error of estimate (SEE) = 26.8 +/- 5.2, 12.5 +/- 5.4 and 9.9 +/- 5.7%, for single scans taken at 40, 50 and 60% of femur length respectively. In comparison, when volume was estimated using multiple MRI scans corresponding to the maximum ACSA of each muscle the estimate was even better [R-2 = 0.95 (P <0.01) and SEE = 4.5 +/- 2.7%]. Substituting ACSA from a single MRI scan at 60% of femur length into a previously determined regression equation allows for an estimation of muscle volume with a 10% error of estimate.

AB - Muscle size is often reported as a single anatomical cross-sectional area (ACSA), rather than volume measured with contiguous MRI scans. However, a single ACSA may provide an inadequate estimate of muscle mass. Therefore, we investigated whether quadriceps muscle volume can be adequately estimated from a single ACSA. In 18 adult males we derived regression equations from which estimates of volume were made. These equations were based on the direct assessment of volume using 11 transverse-plane MRI scans along the entire length of the femur (the gold standard). We estimated volume based on single scans at 40, 50 and 60% of femur length (from the distal end). All estimates of quadriceps volumes were highly correlated to the measured volume and demonstrated a low level of error. R-2 = 0.84, 0.93, 0.90 (all P <0.01), standard error of estimate (SEE) = 26.8 +/- 5.2, 12.5 +/- 5.4 and 9.9 +/- 5.7%, for single scans taken at 40, 50 and 60% of femur length respectively. In comparison, when volume was estimated using multiple MRI scans corresponding to the maximum ACSA of each muscle the estimate was even better [R-2 = 0.95 (P <0.01) and SEE = 4.5 +/- 2.7%]. Substituting ACSA from a single MRI scan at 60% of femur length into a previously determined regression equation allows for an estimation of muscle volume with a 10% error of estimate.

KW - muscle mass

KW - quadriceps volume

KW - anatomical cross-sectional area

U2 - 10.1007/s00421-007-0429-4

DO - 10.1007/s00421-007-0429-4

M3 - Article

C2 - 17342544

VL - 100

SP - 267

EP - 274

JO - European Journal of Applied Physiology

JF - European Journal of Applied Physiology

SN - 1439-6319

ER -