TY - JOUR
T1 - The use of phase inversion temperature (PIT) microemulsion technology to enhance oil utilisation during Streptomyces rimosus fed-batch fermentations to produce oxytetracycline
AU - Papapanagiotou, Panagiotis
AU - Quinn, H
AU - Molitor, JP
AU - Nienow, Alvin
AU - Hewitt, Christopher
PY - 2005/10/1
Y1 - 2005/10/1
N2 - The use of a rapeseed oil emulsion feed, produced by a phase inversion temperature (PIT) process, produced more biomass, gave a 3-fold increase in oil utilisation and a higher oxytetracycline titre but a higher residual oil concentration when compared to a conventional fed-batch Streptomyces rimosus process fed with crude rapeseed oil. Importantly, microbial utilisation of the surfactant was confirmed for the first time.
AB - The use of a rapeseed oil emulsion feed, produced by a phase inversion temperature (PIT) process, produced more biomass, gave a 3-fold increase in oil utilisation and a higher oxytetracycline titre but a higher residual oil concentration when compared to a conventional fed-batch Streptomyces rimosus process fed with crude rapeseed oil. Importantly, microbial utilisation of the surfactant was confirmed for the first time.
KW - Streptomyces rimosus
KW - fed-batch fermentation
KW - PIT micro-emulsion
KW - oxytetracycline
KW - residual oil
UR - http://www.scopus.com/inward/record.url?scp=27144438998&partnerID=8YFLogxK
U2 - 10.1007/s10529-005-2512-4
DO - 10.1007/s10529-005-2512-4
M3 - Article
SN - 1573-6776
VL - 27
SP - 1579
EP - 1585
JO - Biotechnology Letters
JF - Biotechnology Letters
ER -