The T-cell response to haptenated insulins. II. The antibody response

Research output: Contribution to journalArticlepeer-review

Authors

Colleges, School and Institutes

Abstract

As described in an accompanying paper, trinitrophenyl (TNP) modification of pork insulin (PI) at the A1 glycine position allows this molecule to stimulate a proliferative response in H-2b (B10) mice. We now show that this antigen stimulates low IgG responses in the same strain of mice. Our results show that T-cell help and proliferation may therefore be regulated independently.

Details

Original languageEnglish
Pages (from-to)45-8
Number of pages4
JournalImmunology
Volume66
Issue number1
Publication statusPublished - Jan 1989

Keywords

  • Adoptive Transfer, Animals, Antibodies, Antibody Formation, B-Lymphocytes, Cattle, Cell Proliferation, Insulin, Mice, Mice, Inbred Strains, Swine, T-Lymphocytes