Abstract
A large series of plasma cell dyscrasias (n=2207) was examined for translocations which deregulate the MAF genes, t(14;20)(q32;q12) and t(14;16)(q32;q23), and their disease behavior was compared to a group characterized by the t(4;14)(p16;q32) where CCND2 is also up-regulated. The t(14;20) showed low prevalence in myeloma (27/1830, 1.5%) and smoldering myeloma (1/148,
Original language | English |
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Pages (from-to) | 1221-1225 |
Number of pages | 5 |
Journal | Haematologica |
Volume | 95 |
Issue number | 7 |
DOIs | |
Publication status | Published - 1 Jul 2010 |
Keywords
- myeloma
- chromosome abnormality
- plasma cell
- disease progression
- MGUS